A new extracorporeal shock wave lithotripsy technique employing spherical sector shock waves will be evaluated with respect to pulverizing human kidney stones and decreasing tissue damage. Experimental comparisons will be made with a commercial-like elliptic reflector-type, focused shock system. These will use a common electric arc energy supply, test tank, kidney stone and stimulant targets and tissue and ultra-high-resolution piezoelectric polymer shock-pressure-measuring instrumentation. The tests, designed to simulate human treatment conditions in several significant respects, will provide general performance information for the proposed system in controlled comparison with that for the most widely used type of shock wave generator in clinical lithotripters today. The results should provide the essential base for a subsequent Phase II in vivo model animal investigation. This research is expected to lead to a major change in mode of clinical treatment because of the potential for sharp reductions in patient injury, pain and treatment time.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43DK042744-01A1
Application #
3495973
Study Section
Special Emphasis Panel (SSS (B3))
Project Start
1990-09-30
Project End
1991-09-30
Budget Start
1990-09-30
Budget End
1991-09-30
Support Year
1
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Enig Associates, Inc.
Department
Type
DUNS #
City
Silver Spring
State
MD
Country
United States
Zip Code
20904