Continuous near-red light spectroscopy for early warning hypoxic/ischemic stress has the great advantage of simplicity and effica a """"""""trend indicator"""""""", on the one hand, and time-resolved spectroscopic techniques in the picosecond/nanosecond regions give the exact pathle travelled by the photons, on the other. By time sharing light appropriate choice of wavelengths, the absolute hemoglobin concentration be determined in the arteriolar-venular capillary bed. At the same time changes in deoxyhemoglobin due to hypoxic stress can be quantified. Furthermore, and most important, simultaneous use of continuous light at time-resolved spectroscopy at the some point in the tissue affords calibration of the effective optical path of the continuous light method thereby greatly increasing the utility of the latter. [A simple dual wavelength phase modulation spectrophotometer achieves these goals in a compact, economic, efficient and readily marketable device.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43GM042322-01A1
Application #
3498337
Study Section
Special Emphasis Panel (SSS (G))
Project Start
1990-02-01
Project End
1990-07-31
Budget Start
1990-02-01
Budget End
1990-07-31
Support Year
1
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Near Infrared Monitoring, Inc. (NIM)
Department
Type
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19104