The goal of this work is to provide a software workbench for scientists trying to characterize sequenced genes using GeneChips, Micro-arrays or similar technologies. The workbench will allow classification, archiving, analysis and visualization of a variety of experiments. This is important as the current tools are insufficient, and scientists have too much data to analyze manually. This phase I application focuses upon analysis and visualization, particularly for time series and other multiple condition, expression experiment. The visualization includes animation and graphing; the analysis will include cluster analysis, and condition identification, such as """"""""over-expressed in experiments A and B relative to C and D."""""""" We believe this software would contribute to the overall goals of the Human Genome Project by assisting researchers to identify and characterize genes on a large (genomic) scale.

Proposed Commercial Applications

Production of software to aid in gene function identification through expression studies. Production of software to aid in biochemical function identification through expression studies.

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43HG001894-01
Application #
2793677
Study Section
Special Emphasis Panel (ZMH1-NRB-R (01))
Project Start
1999-01-01
Project End
1999-06-30
Budget Start
1999-01-01
Budget End
1999-06-30
Support Year
1
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Silicon Genetics
Department
Type
DUNS #
City
Redwood City
State
CA
Country
United States
Zip Code
94063