A novel class of fluorochemical are proposed as blood substitutes. The proposed compositions will be synthesized, purified, and characterized. Emulsions and other preparations will be prepared and their ability to dissolve oxygen will be determined. The efficacy of the proposed fluorochemicals as blood substitute will be determined using mice. It is expected that some of the proposed fluorochemicals would prevent clearance of the particles by the reticulolendotential system.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43HL042213-01A1
Application #
3501491
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1990-04-01
Project End
1990-12-31
Budget Start
1990-04-01
Budget End
1990-12-31
Support Year
1
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Jp Laboratories, Inc.
Department
Type
DUNS #
City
Piscataway
State
NJ
Country
United States
Zip Code
08854