The investigators propose to develop a diffusion barrier to be used on blood pumps as well as other soft-tissue implants. The barrier is to be provided by a thin Titanium Nitride (TiN) coating deposited on the plastic membranes of implants. The demonstration of the diffusion barrier coating will be carried out using pulsatile blood pumps which are currently under development and designed for long-term use. The investigators describe a unique capability to apply, using a sputtering technique, biocompatible ceramics such as TiN to polymers at room temperature. The resulting coating is reported to be amorphous and tolerates flex and stretch without disruption of the barrier.
The aim of the work is to alleviate what are identified as two of the most significant problems with pulsatile blood pumps, namely, diffusion of fluids from the pump system and diffusion of body fluids into the pump system.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43HL059044-01
Application #
2421515
Study Section
Special Emphasis Panel (ZRG7-SSS-W (05))
Project Start
1997-08-01
Project End
1998-07-31
Budget Start
1997-08-01
Budget End
1998-07-31
Support Year
1
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Medquest Products, Inc.
Department
Type
DUNS #
City
Salt Lake City
State
UT
Country
United States
Zip Code
84103