The goal of this research is to devise automated methods of analyzing the Auditory Brainstem Response (ABR) when it is recorded using three orthogonal channels. The resulting 3-Channel Lissajous Trajectory (3-CLT) shows both linear and planar portions, which will be detected using algorithms tested under realistic conditions of background noise. The 3-CLT methodology is likely to be more sensitive to pathological changes in the auditory nervous system than is the ABR, though the ABR has had extensive use in audiology and neurology as a measure of brainstem normality or abnormality. The automated methods will be designed for microcomputers which are likely to be the basis for evoked response recording systems in the future. At least six companies now produce such systems, primarily for clinical use, but the ABR systems cannot record or analyze the 3-CLT at present, and reliable algorithms are not yet known for the otherwise complex and time-consuming analysis that the 3-CLT requires.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43NS024122-01
Application #
3504105
Study Section
Hearing Research Study Section (HAR)
Project Start
1986-09-01
Project End
1987-02-28
Budget Start
1986-09-01
Budget End
1987-02-28
Support Year
1
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Abratech Corporation
Department
Type
DUNS #
624508917
City
Sausalito
State
CA
Country
United States
Zip Code
94965