Helicobacter Pylori Mucosal Vaccine

Lee, Cynthia K.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Small Business Innovation Research Grants (SBIR) - Phase II (R44)
• Project #: 2R44AI034679-02A1
• Application #: 2069825
• Study Section: Special Emphasis Panel (ZRG7-SSS-4 (02))
• Project Start: 1993-09-30
• Project End: 1997-08-31
• Budget Start: 1995-09-30
• Budget End: 1997-08-31
• Support Year: 2
• Fiscal Year: 1995

Institution

• Name: Acambis, Inc.
• City: Cambridge
• State: MA
• Country: United States
• Zip Code: 02139

Publications

Kleanthous, H; Tibbitts, T J; Gray, H L et al. (2001) Sterilizing immunity against experimental Helicobacter pylori infection is challenge-strain dependent. Vaccine 19:4883-95

Myers, G A; Ermak, T H; Georgakopoulos, K et al. (1999) Oral immunization with recombinant Helicobacter pylori urease confers long-lasting immunity against Helicobacter felis infection. Vaccine 17:1394-403

Kleanthous, H; Myers, G A; Georgakopoulos, K M et al. (1998) Rectal and intranasal immunizations with recombinant urease induce distinct local and serum immune responses in mice and protect against Helicobacter pylori infection. Infect Immun 66:2879-86