Abstract

This is a Shannon Award providing partial support for research projects that fall short of the assigned institute's funding range but are in the margin of excellence. The Shannon award is intended to provide support to test the feasibility of the approach; develop further tests and refine research techniques; perform secondary analysis of available data sets; or conduct discrete projects that can demonstrate the PI's research capabilities or lend additional weight to an already meritorious application. Further scientific data for the CRISP System are unavailable at this time.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
James A. Shannon Director's Award (R55)
Project #
1R55AI030937-01A1
Application #
3509500
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1991-09-30
Project End
1994-09-29
Budget Start
1991-09-30
Budget End
1994-09-29
Support Year
1
Fiscal Year
1991
Total Cost
Indirect Cost

  Institution

Name
University of Pittsburgh
Department
Type
Schools of Public Health
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Etienne, Lucie; Bibollet-Ruche, Frederic; Sudmant, Peter H et al. (2015) The Role of the Antiviral APOBEC3 Gene Family in Protecting Chimpanzees against Lentiviruses from Monkeys. PLoS Pathog 11:e1005149
Etienne, Lucie; Hahn, Beatrice H; Sharp, Paul M et al. (2013) Gene loss and adaptation to hominids underlie the ancient origin of HIV-1. Cell Host Microbe 14:85-92
Etienne, Lucie; Emerman, Michael (2013) The mongoose, the pheasant, the pox, and the retrovirus. PLoS Biol 11:e1001641
Li, Melody M H; Emerman, Michael (2011) Polymorphism in human APOBEC3H affects a phenotype dominant for subcellular localization and antiviral activity. J Virol 85:8197-207
Tareen, Semih U; Emerman, Michael (2011) Human Trim5? has additional activities that are uncoupled from retroviral capsid recognition. Virology 409:113-20
Patel, Maulik R; Emerman, Michael; Malik, Harmit S (2011) Paleovirology - ghosts and gifts of viruses past. Curr Opin Virol 1:304-9
Lim, Efrem S; Malik, Harmit S; Emerman, Michael (2010) Ancient adaptive evolution of tetherin shaped the functions of Vpu and Nef in human immunodeficiency virus and primate lentiviruses. J Virol 84:7124-34
Li, Melody M H; Wu, Lily I; Emerman, Michael (2010) The range of human APOBEC3H sensitivity to lentiviral Vif proteins. J Virol 84:88-95
Emerman, Michael; Malik, Harmit S (2010) Paleovirology--modern consequences of ancient viruses. PLoS Biol 8:e1000301
Lim, Efrem S; Emerman, Michael (2009) Simian immunodeficiency virus SIVagm from African green monkeys does not antagonize endogenous levels of African green monkey tetherin/BST-2. J Virol 83:11673-81

Showing the most recent 10 out of 11 publications