Abstract

This is a Shannon Award providing partial support for research projects that fall short of the assigned institute's funding range but are in the margin of excellence. The Shannon award is intended to provide support to test the feasibility of the approach; develop further tests and refine research techniques; perform secondary analysis of available data sets; or conduct discrete projects that can demonstrate the PI's research capabilities or lend additional weight to an already meritorious application. Further scientific data for the CRISP System are unavailable at this time.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
James A. Shannon Director's Award (R55)
Project #
1R55HG000656-01
Application #
2208947
Study Section
Genome Study Section (GNM)
Project Start
1992-09-07
Project End
1995-08-31
Budget Start
1992-09-07
Budget End
1995-08-31
Support Year
1
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
University of Nevada Reno
Department
Biochemistry
Type
Schools of Medicine
DUNS #
146515460
City
Reno
State
NV
Country
United States
Zip Code
89557

  Publications

Dlakic, M; Harrington, R E (1996) The effects of sequence context on DNA curvature. Proc Natl Acad Sci U S A 93:3847-52
Balagurumoorthy, P; Sakamoto, H; Lewis, M S et al. (1995) Four p53 DNA-binding domain peptides bind natural p53-response elements and bend the DNA. Proc Natl Acad Sci U S A 92:8591-5
Dlakic, M; Harrington, R E (1995) Bending and torsional flexibility of G/C-rich sequences as determined by cyclization assays. J Biol Chem 270:29945-52
Jing, T W; Jeffrey, A M; DeRose, J A et al. (1993) Structure of hydrated oligonucleotides studied by in situ scanning tunneling microscopy. Proc Natl Acad Sci U S A 90:8934-8