Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
High Priority, Short Term Project Award (R56)
Project #
2R56AI028388-13A2
Application #
7283995
Study Section
Pathogenic Eukaryotes Study Section (PTHE)
Program Officer
Duncan, Rory A
Project Start
1991-01-01
Project End
2008-03-31
Budget Start
2006-09-15
Budget End
2008-03-31
Support Year
13
Fiscal Year
2006
Total Cost
$388,958
Indirect Cost

  Institution

Name
Duke University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705

  Publications

Tseng, Hsiang-Kuang; Liu, Chang-Pan; Price, Michael S et al. (2012) Identification of genes from the fungal pathogen Cryptococcus neoformans related to transmigration into the central nervous system. PLoS One 7:e45083
Fang, Wei; Price, Michael S; Toffaletti, Dena L et al. (2012) Pleiotropic effects of deubiquitinating enzyme Ubp5 on growth and pathogenesis of Cryptococcus neoformans. PLoS One 7:e38326
Geunes-Boyer, Scarlett; Beers, Michael F; Perfect, John R et al. (2012) Surfactant protein D facilitates Cryptococcus neoformans infection. Infect Immun 80:2444-53
Ngamskulrungroj, Popchai; Price, Jennifer; Sorrell, Tania et al. (2011) Cryptococcus gattii virulence composite: candidate genes revealed by microarray analysis of high and less virulent Vancouver island outbreak strains. PLoS One 6:e16076
Price, Michael S; Betancourt-Quiroz, Marisol; Price, Jennifer L et al. (2011) Cryptococcus neoformans requires a functional glycolytic pathway for disease but not persistence in the host. MBio 2:e00103-11
Lee, Anthony; Toffaletti, Dena L; Tenor, Jennifer et al. (2010) Survival defects of Cryptococcus neoformans mutants exposed to human cerebrospinal fluid result in attenuated virulence in an experimental model of meningitis. Infect Immun 78:4213-25
LaFayette, Shantelle L; Collins, Cathy; Zaas, Aimee K et al. (2010) PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90. PLoS Pathog 6:e1001069
Singh, Sheena D; Robbins, Nicole; Zaas, Aimee K et al. (2009) Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin. PLoS Pathog 5:e1000532
Geunes-Boyer, Scarlett; Oliver, Timothy N; Janbon, Guilhem et al. (2009) Surfactant protein D increases phagocytosis of hypocapsular Cryptococcus neoformans by murine macrophages and enhances fungal survival. Infect Immun 77:2783-94
Shapiro, Rebecca S; Uppuluri, Priya; Zaas, Aimee K et al. (2009) Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling. Curr Biol 19:621-9

Showing the most recent 10 out of 12 publications