Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
High Priority, Short Term Project Award (R56)
Project #
2R56AI033600-11A1
Application #
7071473
Study Section
Molecular Genetics B Study Section (MGB)
Program Officer
Nabavi, Nasrin N
Project Start
1993-02-01
Project End
2006-02-14
Budget Start
2005-07-15
Budget End
2006-02-14
Support Year
11
Fiscal Year
2005
Total Cost
$436,979
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Panas, Marc D; Schulte, Tim; Thaa, Bastian et al. (2015) Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation. PLoS Pathog 11:e1004659
Stoecklin, Georg; Kedersha, Nancy (2013) Relationship of GW/P-bodies with stress granules. Adv Exp Med Biol 768:197-211
Fujimura, Ken; Sasaki, Atsuo T; Anderson, Paul (2012) Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules. Nucleic Acids Res 40:8099-110
Emara, Mohamed M; Fujimura, Ken; Sciaranghella, Daniele et al. (2012) Hydrogen peroxide induces stress granule formation independent of eIF2ýý phosphorylation. Biochem Biophys Res Commun 423:763-9
Ivanov, Pavel; Emara, Mohamed M; Villen, Judit et al. (2011) Angiogenin-induced tRNA fragments inhibit translation initiation. Mol Cell 43:613-23
Simpson-Holley, M; Kedersha, N; Dower, K et al. (2011) Formation of antiviral cytoplasmic granules during orthopoxvirus infection. J Virol 85:1581-93
Shih, Joseph D; Waks, Zeev; Kedersha, Nancy et al. (2011) Visualization of single mRNAs reveals temporal association of proteins with microRNA-regulated mRNA. Nucleic Acids Res 39:7740-9
Emara, Mohamed M; Ivanov, Pavel; Hickman, Tyler et al. (2010) Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly. J Biol Chem 285:10959-68
Li, Chi Ho; Ohn, Takbum; Ivanov, Pavel et al. (2010) eIF5A promotes translation elongation, polysome disassembly and stress granule assembly. PLoS One 5:e9942
Kedersha, Nancy; Anderson, Paul (2009) Regulation of translation by stress granules and processing bodies. Prog Mol Biol Transl Sci 90:155-85

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