Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
High Priority, Short Term Project Award (R56)
Project #
2R56DK021739-24
Application #
7284768
Study Section
Macromolecular Structure and Function A Study Section (MSFA)
Program Officer
Wright, Daniel G
Project Start
1978-12-01
Project End
2007-06-30
Budget Start
2006-09-15
Budget End
2007-06-30
Support Year
24
Fiscal Year
2006
Total Cost
$114,000
Indirect Cost

  Institution

Name
University of Vermont & St Agric College
Department
Biochemistry
Type
Schools of Medicine
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405

  Publications

Rooijakkers, Suzan H M; Rasmussen, Suzanne L; McGillivray, Shauna M et al. (2010) Human transferrin confers serum resistance against Bacillus anthracis. J Biol Chem 285:27609-13
Yoon, Dennis J; Kwan, Byron H; Chao, Felix C et al. (2010) Intratumoral therapy of glioblastoma multiforme using genetically engineered transferrin for drug delivery. Cancer Res 70:4520-7
Kovac, Suzana; Ferrand, Audrey; Estève, Jean-Pierre et al. (2009) Definition of the residues required for the interaction between glycine-extended gastrin and transferrin in vitro. FEBS J 276:4866-74
Yoon, Dennis J; Chu, David S H; Ng, Christopher W et al. (2009) Genetically engineering transferrin to improve its in vitro ability to deliver cytotoxins. J Control Release 133:178-84
James, Nicholas G; Byrne, Shaina L; Mason, Anne B (2009) Incorporation of 5-hydroxytryptophan into transferrin and its receptor allows assignment of the pH induced changes in intrinsic fluorescence when iron is released. Biochim Biophys Acta 1794:532-40
Byrne, Shaina L; Mason, Anne B (2009) Human serum transferrin: a tale of two lobes. Urea gel and steady state fluorescence analysis of recombinant transferrins as a function of pH, time, and the soluble portion of the transferrin receptor. J Biol Inorg Chem 14:771-81