Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
High Priority, Short Term Project Award (R56)
Project #
2R56HL036365-21
Application #
7484385
Study Section
Hemostasis and Thrombosis Study Section (HT)
Program Officer
Link, Rebecca P
Project Start
1985-07-01
Project End
2008-08-19
Budget Start
2007-08-20
Budget End
2008-08-19
Support Year
21
Fiscal Year
2007
Total Cost
$355,750
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Type
Other Domestic Higher Education
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Vadivel, Kanagasabai; Agah, Sayeh; Messer, Amanda S et al. (2013) Structural and functional studies of ?-carboxyglutamic acid domains of factor VIIa and activated Protein C: role of magnesium at physiological calcium. J Mol Biol 425:1961-1981
Geng, Y; Verhamme, I M; Sun, M F et al. (2013) Analysis of the factor XI variant Arg184Gly suggests a structural basis for factor IX binding to factor XIa. J Thromb Haemost 11:1374-84
Geng, Yipeng; Verhamme, Ingrid M; Messer, Amanda et al. (2012) A sequential mechanism for exosite-mediated factor IX activation by factor XIa. J Biol Chem 287:38200-9
Vadivel, Kanagasabai; Bajaj, S Paul (2012) Structural biology of factor VIIa/tissue factor initiated coagulation. Front Biosci (Landmark Ed) 17:2476-94
Messer, A S; Velander, W H; Bajaj, S P (2009) Contribution of magnesium in binding of factor IXa to the phospholipid surface: implications for vitamin K-dependent coagulation proteins. J Thromb Haemost 7:2151-3
Agah, S; Bajaj, S P (2009) Role of magnesium in factor XIa catalyzed activation of factor IX: calcium binding to factor IX under physiologic magnesium. J Thromb Haemost 7:1426-8