Increasing racial and ethnic diversity is the hallmark of United States demography. For example, in 2011, 13% of the population classified themselves as African American and nearly 17% classified themselves of Hispanic or Latino origin and these percentages are expected to increase substantially in the near future. Diversity among older individuals is similarly increasing with self-identified minorities expected to increase to 20% with most minority adults being of Latino origin by 2020. Increasing diversity of the population has significant

Public Health Relevance

By leveraging the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) cohort, we plan to examine the impact of disparities in vascular risk factors on brain health utilizing cutting edge MRI techniques within a large, understudied population of diverse Latinos spanning the age range of risk for stroke and dementia. We will also characterize the biological substrates of stroke, MCI and AD among the various racial admixtures in this deeply phenotyped cohort.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Multi-Year Funded Research Project Grant (RF1)
Project #
1RF1AG054548-01
Application #
9220521
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Anderson, Dallas
Project Start
2017-07-15
Project End
2022-06-30
Budget Start
2017-07-15
Budget End
2022-06-30
Support Year
1
Fiscal Year
2017
Total Cost
Indirect Cost
Name
University of California Davis
Department
Neurology
Type
Schools of Medicine
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
González, Hector M; Tarraf, Wassim; Harrison, Kimystian et al. (2018) Midlife cardiovascular health and 20-year cognitive decline: Atherosclerosis Risk in Communities Study results. Alzheimers Dement 14:579-589
González, Hector M; Tarraf, Wassim; Vásquez, Priscilla et al. (2018) Metabolic Syndrome and Neurocognition Among Diverse Middle-Aged and Older Hispanics/Latinos: HCHS/SOL Results. Diabetes Care 41:1501-1509