Abstract

The long-term objectives of the MBRS Program, housed in the Graduate School, will continue to focus on: 1) enhancing the participating faculty's competitive ability to obtain mainstream research support; and 2) to increase the number of minority investigators entering biomedical science fields. Other objectives are to provide a multi-discipline institutional support-base for biomedical studies which will enhance a large segment of departments. In this competing renewal application, 22 subprojects are included from 32 faculty investigators in the departments of Biochemistry, Botany, Chemistry, Communication Sciences, Genetics, Physical Education, Physiology, Psychology, and Zoology. The program includes six (6) Associate Investigators indicating competitive research programs as well as enhanced training capability. Nine (9) new subprojects are included in this application of which three (3) are from junior faculty. The research areas include at least three (3) molecular biology projects as well as three (3) projects in the behavioral effects of health related abnormalities. Twenty-nine graduate and eight (8) undergraduate students are required as co-participants on the various subprojects.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
5S06GM008016-21
Application #
3513137
Study Section
Minority Programs Review Committee (MPRC)
Project Start
1977-06-01
Project End
1994-07-31
Budget Start
1991-08-15
Budget End
1992-07-31
Support Year
21
Fiscal Year
1991
Total Cost
Indirect Cost

  Institution

Name
Howard University
Department
Type
Other Domestic Higher Education
DUNS #
056282296
City
Washington
State
DC
Country
United States
Zip Code
20059

  Publications

Faruque, Mezbah U; Chen, Guanjie; Doumatey, Ayo P et al. (2017) Transferability of genome-wide associated loci for asthma in African Americans. J Asthma 54:1-8
Johnston, Henry Richard; Hu, Yi-Juan; Gao, Jingjing et al. (2017) Identifying tagging SNPs for African specific genetic variation from the African Diaspora Genome. Sci Rep 7:46398
Kessler, Michael D; Yerges-Armstrong, Laura; Taub, Margaret A et al. (2016) Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry. Nat Commun 7:12521
Liu, Ching-Ti; Raghavan, Sridharan; Maruthur, Nisa et al. (2016) Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. Am J Hum Genet 99:56-75
Rand, Kristin A; Rohland, Nadin; Tandon, Arti et al. (2016) Whole-exome sequencing of over 4100 men of African ancestry and prostate cancer risk. Hum Mol Genet 25:371-81
Mathias, Rasika Ann; Taub, Margaret A; Gignoux, Christopher R et al. (2016) A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome. Nat Commun 7:12522
Ehret, Georg B (see original citation for additional authors) (2016) The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nat Genet 48:1171-1184
Kurian, P; Dunston, G; Lindesay, J (2016) How quantum entanglement in DNA synchronizes double-strand breakage by type II restriction endonucleases. J Theor Biol 391:102-12
Ogunjirin, Adebowale E; Fortunak, Joseph M; Brown, LaVerne L et al. (2015) Competition, Selectivity and Efficacy of Analogs of A-84543 for Nicotinic Acetylcholine Receptors with Repositioning of Pyridine Nitrogen. Neurochem Res 40:2131-42
Winchester, Danyelle; Ricks-Santi, Luisel; Mason, Tshela et al. (2015) SPINK1 Promoter Variants Are Associated with Prostate Cancer Predisposing Alterations in Benign Prostatic Hyperplasia Patients. Anticancer Res 35:3811-9

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