In the past two decades, different types of lasers have been used for various medical/surgical procedures but lasers in Ophthalmology have always enjoyed a unique role since they offer new and innovative surgical capabilities to the ophthalmologist. Recently, """"""""Excimer Lasers"""""""" such as Argon Fluoride and Krypton Fluoride have gained much enthusiastic support due to their capability of photoabilative tissue decomposition. There is ongoing research to detect the efficacy of this laser in making corneal incisions and keratorefractive surgery inspite of some newly discovered side effects. Nitrogen laser pumped dye laser coupled with frequency doubling technique can deliver ultra-violet laser energy in the wavelength range 250-330 nm. Its potential clinical use in the medical field has not yet been explored. The purpose of this research is to explore the capabilities of tunable ultra-violet radiation from a frequency-doubled Nitrogen pumped dye laser in potential eye surgery and establish optimum wavelengths for various ophthalmic surgical procedures.

Project Start
Project End
Budget Start
Budget End
Support Year
20
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Jackson State University
Department
Type
DUNS #
044507085
City
Jackson
State
MS
Country
United States
Zip Code
39217
Beqa, Lule; Fan, Zhen; Singh, Anant Kumar et al. (2011) Gold nano-popcorn attached SWCNT hybrid nanomaterial for targeted diagnosis and photothermal therapy of human breast cancer cells. ACS Appl Mater Interfaces 3:3316-24
Khan, Sadia Afrin; Singh, Anant K; Senapati, Dulal et al. (2011) Targeted highly sensitive detection of multi-drug resistant Salmonella DT104 using gold nanoparticles. Chem Commun (Camb) 47:9444-6
Singh, Anant K; Lu, Wentong; Senapati, Dulal et al. (2011) Long-range nanoparticle surface-energy-transfer ruler for monitoring photothermal therapy response. Small 7:2517-25
Huang, Yong; Zhao, Shulin; Shi, Ming et al. (2010) Chemiluminescent immunoassay of thyroxine enhanced by microchip electrophoresis. Anal Biochem 399:72-7
Wang, Shuguang; Singh, Anant K; Senapati, Dulal et al. (2010) Rapid colorimetric identification and targeted photothermal lysis of Salmonella bacteria by using bioconjugated oval-shaped gold nanoparticles. Chemistry 16:5600-6
Lu, Wentong; Singh, Anant Kumar; Khan, Sadia Afrin et al. (2010) Gold nano-popcorn-based targeted diagnosis, nanotherapy treatment, and in situ monitoring of photothermal therapy response of prostate cancer cells using surface-enhanced Raman spectroscopy. J Am Chem Soc 132:18103-14
Lu, Wentong; Arumugam, Sri Ranjini; Senapati, Dulal et al. (2010) Multifunctional oval-shaped gold-nanoparticle-based selective detection of breast cancer cells using simple colorimetric and highly sensitive two-photon scattering assay. ACS Nano 4:1739-49
Dadiboyena, Sureshbabu; Valente, Edward J; Hamme 2nd, Ashton T (2010) Synthesis of Novel Pyrazoles via [2+3]-Dipolar Cycloaddition Using Alkyne Surrogates. Tetrahedron Lett 51:1341
Stewart, Gernerique; Smith, Keonia; Chornes, Ashley et al. (2010) PHOTOCHEMICAL REACTION OF NITRO-POLYCYCLIC AROMATIC HYDROCARBONS: EFFECT BY SOLVENT AND STRUCTURE. Environ Chem Lett 8:301-306
Zhao, Shulin; Huang, Yong; Shi, Ming et al. (2010) Chemiluminescence resonance energy transfer-based detection for microchip electrophoresis. Anal Chem 82:2036-41

Showing the most recent 10 out of 119 publications