This project will examine how women's health behaviors vary across the menstrual cycle. It is well documented that women behave differently during the various phases of their menstrual cycles but no one has examined how or whether their behaviors covary with each other. Women will be asked to keep daily records of their exercise, eating, sexual and health behaviors along with a profile of their mental well-being. These data will be analyzed across independent variables which focus on whether or not sperm are entering the female's reproductive system and whether females have altered their normal hormone profiles by taking birth control pills or receiving depo-provera shots. Additionally, subjects' immune system responses, in terms of saliva and menstrual IgA and menstrual IgM and leukocyte numbers, and stress responses, in terms of saliva cortisol levels, will be obtained at five different phases of their cycles. By the project's end, we will be able to construct a profile of how the health of women varies across their menstrual cycle and how it is affected by their reproductive behavior and by behaviors that alter their normal hormone profiles. These data are needed so that not only can physicians be trained to better treat females, but females can also learn more about their normal health patterns.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
2S06GM008073-33
Application #
6821134
Study Section
Minority Programs Review Committee (MPRC)
Project Start
2004-07-01
Project End
2008-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
33
Fiscal Year
2004
Total Cost
$172,029
Indirect Cost
Name
University of Hawaii at Hilo
Department
Type
DUNS #
195738039
City
Hilo
State
HI
Country
United States
Zip Code
96720
Mishra, Gita D; Chung, Hsin-Fang; Pandeya, Nirmala et al. (2016) The InterLACE study: Design, data harmonization and characteristics across 20 studies on women's health. Maturitas 92:176-185
Morrison, Lynn A; Brown, Daniel E; Sievert, Lynnette L et al. (2014) Voices from the Hilo Women's Health Study: talking story about menopause. Health Care Women Int 35:529-48
Sievert, Lynnette Leidy; Murphy, Lorna; Morrison, Lynn A et al. (2013) Age at menopause and determinants of hysterectomy and menopause in a multi-ethnic community: the Hilo Women's Health Study. Maturitas 76:334-41
Van Berge-Landry, Helene; James, Gary D; Brown, Daniel E (2013) Relationships between diurnal changes in blood pressure and catecholamines among Filipino-American and European-American women. Am J Hum Biol 25:431-3
Reza, Angela; Sievert, Lynnette Leidy; Rahberg, Nichole et al. (2012) Prevalence and determinants of headaches in Hawaii: the Hilo Women's Health Study. Ann Hum Biol 39:305-14
Stringer, Kate; Kerpelman, Jennifer; Skorikov, Vladimir (2012) A longitudinal examination of career preparation and adjustment during the transition from high school. Dev Psychol 48:1343-54
Brown, Daniel E; Sievert, Lynnette L; Morrison, Lynn A et al. (2011) Relationship between hot flashes and ambulatory blood pressure: the Hilo women's health study. Psychosom Med 73:166-72
Morrison, Lynn A; Larkspur, Louona; Calibuso, Marites J et al. (2010) Women's attitudes about menstruation and associated health and behavioral characteristics. Am J Health Behav 34:90-100
Morrison, Lynn A; Sievert, Lynnette L; Brown, Daniel E et al. (2010) Relationships between menstrual and menopausal attitudes and associated demographic and health characteristics: the Hilo Women's Health Study. Women Health 50:397-413
Sievert, Lynnette L; Reza, Angela; Mills, Phoebe et al. (2010) Diurnal rhythm and concordance between objective and subjective hot flashes: the Hilo Women's Health Study. Menopause 17:471-9

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