In keeping with the goals and the major objective of the MBRS program to increase the number of minority (biomedical) research scientist in the U.S. in order to help to retrieve the inequities of minority representation in the biomedical and behavioral fields and disciplines, and further to carry out the mission of the NIH to assist in the alleviation, amelioration and cure of human health and disease, the Tuskegee University MBRS program plans to accomplish the following objectives. (1) To train students in the fundamental (biomedical) research procedures, protocols and rational in order for them to utilize these methods in advanced and further research, alone or in collaboration with other colleagues. (2) To encourage and facilitate research projects in line with the overall objectives above in which students, support personnel and peer colleagues may participate to research the objectives of the individual projects. (3) To encourage and promote faculty members in the development and maturation of their individual research specialties; in the cure of human illness and disease and in the care, maintenance and welfare of human health. (4) To provide and expand the facilities and atmosphere of a research milieu in which the above objectives may flourish. (5) To encourage the more seasoned and experienced investigator to apply for the more competitive grant from other NIH categorical institutes as well as other federal agencies such as NSF, USDA, etc. (6) To assist in the planning and implementation of a new Ph.D. program in the Life Sciences.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
5S06GM008091-29
Application #
6179875
Study Section
Minority Programs Review Committee (MPRC)
Project Start
1978-06-01
Project End
2002-05-31
Budget Start
2000-06-01
Budget End
2001-05-31
Support Year
29
Fiscal Year
2000
Total Cost
$417,179
Indirect Cost
Name
Tuskegee University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
128214178
City
Tuskegee
State
AL
Country
United States
Zip Code
36088
Mathews, Ensa; Braden, Tim D; Williams, Carol S et al. (2009) Mal-development of the penis and loss of fertility in male rats treated neonatally with female contraceptive 17alpha-ethinyl estradiol: a dose-response study and a comparative study with a known estrogenic teratogen diethylstilbestrol. Toxicol Sci 112:331-43
Goyal, H O; Braden, T D; Williams, C S et al. (2009) Estrogen-induced developmental disorders of the rat penis involve both estrogen receptor (ESR)- and androgen receptor (AR)-mediated pathways. Biol Reprod 81:507-16
Cooper, Marvis S; Reeve Jr, Joseph R; Abdalla, Mohamed O et al. (2008) Cholecystokinin-33 is more effective than cholecystokinin-8 in inhibiting food intake and in stimulating the myenteric plexus and dorsal vagal complex. Brain Res 1205:27-35
Raboin, Shannon J; Reeve Jr, Joseph R; Cooper, Marvis S et al. (2008) Activation of submucosal but not myenteric plexus of the gastrointestinal tract accompanies reduction of food intake by camostat. Regul Pept 150:73-80
Cooper, Marvis S; Reeve Jr, Joseph R; Raboin, Shannon J et al. (2008) Cholecystokinin-58 and cholecystokinin-8 produce similar but not identical activations of myenteric plexus and dorsal vagal complex. Regul Pept 148:88-94
Goyal, H O; Braden, T D; Williams, C S et al. (2007) Role of estrogen in induction of penile dysmorphogenesis: a review. Reproduction 134:199-208
Goyal, H O; Braden, T D; Cooke, P S et al. (2007) Estrogen receptor alpha mediates estrogen-inducible abnormalities in the developing penis. Reproduction 133:1057-67
Sullivan, Cherese N; Raboin, Shannon J; Gulley, Stephen et al. (2007) Endogenous cholecystokinin reduces food intake and increases Fos-like immunoreactivity in the dorsal vagal complex but not in the myenteric plexus by CCK1 receptor in the adult rat. Am J Physiol Regul Integr Comp Physiol 292:R1071-80
Raboin, Shannon J; Gulley, Stephen; Henley, Sheryce C et al. (2006) Atropine methyl nitrate increases myenteric but not dorsal vagal complex Fos-like immunoreactivity in the rat. Physiol Behav 88:448-52
Raboin, Shannon J; Gulley, Stephen; Henley, Sheryce C et al. (2006) Effect of sympathectomy and demedullation on increased myenteric and dorsal vagal complex Fos-like immunoreactivity by cholecystokinin-8. Regul Pept 134:141-8

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