Abstract

This study will test an intervention to reduce sexual risk behaviors in a high risk impaired population: home-less men with mental illness. Two hundred participants will be recruited from a psychiatric program in a shelter for homeless men located in Nashville, Tennessee. The majority will be African Americans, have a chronic psychotic disorder, and a co- morbid substance use disorder. In a randomized clinical trial, will be assigned to an experimental cognitive-behavioral or a control intervention, and followed up over 18 months. The experimental intervention, Sex, Games, and Videotapes, SEXG (Susser et al., 1994) will be comprised of 6 sessions. The control intervention will be a one session HIV educational program. Sexual risk behavior will be the primary outcome. Experimental and control groups will be compared with respect to the mean scores on a sexual risk index. The maintenance of sexual risk behavior resulting the SEXG intervention and the control curriculum will be assessed at six week intervals for a period of 18 months.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
5S06GM008092-25
Application #
6107111
Study Section
Project Start
1999-06-01
Project End
2000-05-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
25
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
Tennessee State University
Department
Type
DUNS #
City
Nashville
State
TN
Country
United States
Zip Code
37209

  Publications

Rana, Krupa; Whalen, Margaret (2015) Activation of protein kinase C and protein kinase D in human natural killer cells: effects of tributyltin, dibutyltin, and tetrabromobisphenol A. Toxicol Mech Methods 25:680-8
Hurd-Brown, Tasia; Udoji, Felicia; Martin, Tamara et al. (2013) Effects of DDT and triclosan on tumor-cell binding capacity and cell-surface protein expression of human natural killer cells. J Appl Toxicol 33:495-502
Sharow, Kyle A; Temkin, Boris; Asson-Batres, Mary Ann (2012) Retinoic acid stability in stem cell cultures. Int J Dev Biol 56:273-8
Hurd, Tasia; Walker, Jasmine; Whalen, Margaret M (2012) Pentachlorophenol decreases tumor-cell-binding capacity and cell-surface protein expression of human natural killer cells. J Appl Toxicol 32:627-34
Taylor, Thyneice R; Whalen, Margaret M (2011) Ziram activates mitogen-activated protein kinases and decreases cytolytic protein levels in human natural killer cells. Toxicol Mech Methods 21:577-84
Buchanan, FaMitah Q; Rochette-Egly, Cecile; Asson-Batres, Mary Ann (2011) Detection of variable levels of RAR? and RAR? proteins in pluripotent and differentiating mouse embryonal carcinoma and mouse embryonic stem cells. Cell Tissue Res 346:43-51
Hurd, Tasia; Whalen, Margaret M (2011) Tetrabromobisphenol A decreases cell-surface proteins involved in human natural killer (NK) cell-dependent target cell lysis. J Immunotoxicol 8:219-27
Udoji, Felicia; Martin, Tamara; Etherton, Rachel et al. (2010) Immunosuppressive effects of triclosan, nonylphenol, and DDT on human natural killer cells in vitro. J Immunotoxicol 7:205-12
Abraha, Abraham B; Rana, Krupa; Whalen, Margaret M (2010) Role of protein kinase C in TBT-induced inhibition of lytic function and MAPK activation in human natural killer cells. Arch Environ Contam Toxicol 59:661-9
Hinkson, Natasha C; Whalen, Margaret M (2010) Hexabromocyclododecane decreases tumor-cell-binding capacity and cell-surface protein expression of human natural killer cells. J Appl Toxicol 30:302-9

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