Abstract

The assessment of the environmental applications of novel synthetic supramolecular materials derived from cyclodextrins is proposed. The ability of water-insoluble polymer-anchored cyclodextrins to remove organic compounds from water through inclusion complexation with cyclodextrins containing tethered indicator moieties to act as molecular sensors to detect organics in water will be investigated. The non- covalent interactions and the disposition of the substrate (guest) and receptor (host) in these supramolecular assemblies will be studied by NOE NMR techniques.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
5S06GM008168-16
Application #
3734436
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
16
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
City College of New York
Department
Type
DUNS #
603503991
City
New York
State
NY
Country
United States
Zip Code
10031

  Publications

Fried, Eric S; Li, Yue-Ming; Gilchrist, M Lane (2017) Phase Composition Control in Microsphere-Supported Biomembrane Systems. Langmuir 33:3028-3039
Beck, Cade; Singh, Tanya; Farooqi, Angela et al. (2016) Controlled microfluidics to examine growth-factor induced migration of neural progenitors in the Drosophila visual system. J Neurosci Methods 262:32-40
Gilchrist, M Lane; Ahn, Kwangwook; Li, Yue-Ming (2016) Imaging and Functional Analysis of ?-Secretase and Substrate in a Proteolipobead System with an Activity-Based Probe. Anal Chem 88:1303-11
Fried, Eric S; Luchan, Joshua; Gilchrist, M Lane (2016) Biodegradable, Tethered Lipid Bilayer-Microsphere Systems with Membrane-Integrated ?-Helical Peptide Anchors. Langmuir 32:3470-5
Banerjee, Shaibal; Sinha, Saikat; Pradhan, Padmanava et al. (2016) Regiospecifically Fluorinated Polycyclic Aromatic Hydrocarbons via Julia-Kocienski Olefination and Oxidative Photocyclization. Effect of Fluorine Atom Substitution on Molecular Shape. J Org Chem 81:3983-93
Salas-Ramirez, Kaliris Y; Bagnall, Ciara; Frias, Leslie et al. (2015) Doxorubicin and cyclophosphamide induce cognitive dysfunction and activate the ERK and AKT signaling pathways. Behav Brain Res 292:133-41
Thomson, Paul F; Parrish, Damon; Pradhan, Padmanava et al. (2015) Modular, Metal-Catalyzed Cycloisomerization Approach to Angularly Fused Polycyclic Aromatic Hydrocarbons and Their Oxidized Derivatives. J Org Chem 80:7435-46
Small, Chiyedza; Ramroop, Johnny; Otazo, Maria et al. (2014) An unexpected link between notch signaling and ROS in restricting the differentiation of hematopoietic progenitors in Drosophila. Genetics 197:471-83
Zhong, Lina; Tu, Raymond; Gilchrist, M Lane (2013) Tether-supported biomembranes with ?-helical peptide-based anchoring constructs. Langmuir 29:299-307
Guleyupoglu, Berkan; Schestatsky, Pedro; Edwards, Dylan et al. (2013) Classification of methods in transcranial electrical stimulation (tES) and evolving strategy from historical approaches to contemporary innovations. J Neurosci Methods 219:297-311

Showing the most recent 10 out of 94 publications