The continuing long=-range objective of the MBRS Program at the University of Puerto Rico Medical Sciences Campus (MSC-MBRS) is targeted to achieve two principal goals; to help faculty develop a productive research project and to stimulate Hispanic students to choose a biomedical career. These goals, mutually interdependent, are pursued by facilitating the ongoing research projects and providing productive research environment ot stimulate enthusiastic students. Through the support of MBRS, investigators accumulate enough data to publish in peer-review journals and apply for independent research support. The Program focuses to encourage the participation of young investigators with the expectation that this support empowers them to compete on a more equal basis with researchers from more gifted institutions. Students from the Sch of Med Graduate Sch, the Sch of Pharm and undergraduates from the departments of Chemistry and Biology of the University of Puerto Rico, Rio Piedras Campus participate ina the Program.
We aim to encourage their long-term interest in biomedical research and careers by providing quality research experience. The student participants in the MSC-MBRS Program have achieved significant goals including acceptance on major institutions, such as Albert Einstein Sch of Med, University of Pittsburgh and Columbia University. Our application includes subproposls for 16 investigators of which three are associate investigators. The investigators are from the Schools of Medicine, and Pharmacy. The projects cover the areas of molecular biology, renal physiology, experimental therapeutics, toxicology, microbiology, parasite immunology, biochemistry, immunology and neurobiology.
| Rijpma, Sanna R; van der Velden, Maarten; González-Pons, Maria et al. (2016) Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites. Cell Microbiol 18:369-83 |
| Padín-Irizarry, Vivian; Colón-Lorenzo, Emilee E; Vega-Rodríguez, Joel et al. (2016) Glutathione-deficient Plasmodium berghei parasites exhibit growth delay and nuclear DNA damage. Free Radic Biol Med 95:43-54 |
| Jardón, Javier; Izquierdo, Natalio J; Renta, Jessica Y et al. (2016) Ocular Findings in Patients with the Hermansky-Pudlak Syndrome (Types 1 and 3). Ophthalmic Genet 37:89-94 |
| Rivera-Peña, Bianca; Ruíz-Fullana, Francisco J; Vélez-Reyes, Germán L et al. (2016) HPV-16 infection modifies overall survival of Puerto Rican HNSCC patients. Infect Agent Cancer 11:47 |
| Velásquez-Martínez, Maria C; Vázquez-Torres, Rafael; Rojas, Legier V et al. (2015) Alpha-1 adrenoreceptors modulate GABA release onto ventral tegmental area dopamine neurons. Neuropharmacology 88:110-21 |
| Vega-Rodríguez, Joel; Pastrana-Mena, Rebecca; Crespo-Lladó, Keila N et al. (2015) Implications of Glutathione Levels in the Plasmodium berghei Response to Chloroquine and Artemisinin. PLoS One 10:e0128212 |
| Zenón, Frances; Cantres-Rosario, Yisel; Adiga, Radhika et al. (2015) HIV-infected microglia mediate cathepsin B-induced neurotoxicity. J Neurovirol 21:544-58 |
| Segarra, Annabell C; Torres-Díaz, Yvonne M; Silva, Richard D et al. (2014) Estrogen receptors mediate estradiol's effect on sensitization and CPP to cocaine in female rats: role of contextual cues. Horm Behav 65:77-87 |
| Ortiz, A P; Unger, E R; Muñoz, C et al. (2014) Cross-sectional study of HPV-16 infection in a population-based subsample of Hispanic adults. BMJ Open 4:e004203 |
| Rosas, Odrick R; Torrado, Aranza I; Santiago, Jose M et al. (2014) Long-term treatment with PP2 after spinal cord injury resulted in functional locomotor recovery and increased spared tissue. Neural Regen Res 9:2164-73 |
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