The long-term objective of the MJBRS SCORE Program, Medical Sciences Campus, University of Puerto Rico (MSC-UPR) is to develop productive health-related research programs among faculty and to contribute to a supportive campus research environment. Its primary goal is to provide faculty an opportunity to generate sufficient data to publish in internationally recognized peer-reviewed journals and to support grant applications for independent research. In addition to opportunities for faculty, the MBRS SCORE Program, through its close coordination with the MBRS RISE Program, provides opportunities for undergraduate and graduate students at MSC-UPR (98% of students are Hispanic) to participate in quality research. Thus, a secondary effect of the MBRS SCORE Program is to stimulate under-represented minority students to pursue careers in biomedically relevant research. To further these goals, the program encourages research development among all Medical Sciences Campus faculty. The MBRS SCORE Program provides faculty with the necessary support to develop their full potential and to compete successfully with investigators at more established research institutions. It is anticipated that research productivity among MBRS SCORE faculty will increase by 10% per year for publications in peer-reviewed journals and by the third year of the found founding period all participating faculty will submit grant applications for individual research support. The 24 projects (19 regular and 5 pilot) that make up this program include both basic and clinical biomedically related research projects from faculty in the Schools of Medicine, Pharmacy, and Allied Health. It is noteworthy that the populations in the clinical studies are groups specifically targeted for inclusion in NIH-funded studies, i.e., Hispanics, women, and children. The diverse projects include such areas as congenital malformations, genetic disorders, diabetes, and menopause; molecular biology, biochemistry, physiology, and cell biology; ; microbiology, immunology, and neurobiology; and Dengue vaccine, malaria, TB, and HIV.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
3S06GM008224-18S3
Application #
6704827
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Toliver, Adolphus
Project Start
1985-05-01
Project End
2004-07-31
Budget Start
2002-08-01
Budget End
2003-07-31
Support Year
18
Fiscal Year
2003
Total Cost
$34,270
Indirect Cost
Name
University of Puerto Rico Med Sciences
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
948108063
City
San Juan
State
PR
Country
United States
Zip Code
00936
Rijpma, Sanna R; van der Velden, Maarten; González-Pons, Maria et al. (2016) Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites. Cell Microbiol 18:369-83
Padín-Irizarry, Vivian; Colón-Lorenzo, Emilee E; Vega-Rodríguez, Joel et al. (2016) Glutathione-deficient Plasmodium berghei parasites exhibit growth delay and nuclear DNA damage. Free Radic Biol Med 95:43-54
Jardón, Javier; Izquierdo, Natalio J; Renta, Jessica Y et al. (2016) Ocular Findings in Patients with the Hermansky-Pudlak Syndrome (Types 1 and 3). Ophthalmic Genet 37:89-94
Rivera-Peña, Bianca; Ruíz-Fullana, Francisco J; Vélez-Reyes, Germán L et al. (2016) HPV-16 infection modifies overall survival of Puerto Rican HNSCC patients. Infect Agent Cancer 11:47
Velásquez-Martínez, Maria C; Vázquez-Torres, Rafael; Rojas, Legier V et al. (2015) Alpha-1 adrenoreceptors modulate GABA release onto ventral tegmental area dopamine neurons. Neuropharmacology 88:110-21
Vega-Rodríguez, Joel; Pastrana-Mena, Rebecca; Crespo-Lladó, Keila N et al. (2015) Implications of Glutathione Levels in the Plasmodium berghei Response to Chloroquine and Artemisinin. PLoS One 10:e0128212
Zenón, Frances; Cantres-Rosario, Yisel; Adiga, Radhika et al. (2015) HIV-infected microglia mediate cathepsin B-induced neurotoxicity. J Neurovirol 21:544-58
Ortiz, A P; Unger, E R; Muñoz, C et al. (2014) Cross-sectional study of HPV-16 infection in a population-based subsample of Hispanic adults. BMJ Open 4:e004203
Rosas, Odrick R; Torrado, Aranza I; Santiago, Jose M et al. (2014) Long-term treatment with PP2 after spinal cord injury resulted in functional locomotor recovery and increased spared tissue. Neural Regen Res 9:2164-73
Mosquera, Laurivette; Colón, Jennifer M; Santiago, José M et al. (2014) Tamoxifen and estradiol improved locomotor function and increased spared tissue in rats after spinal cord injury: their antioxidant effect and role of estrogen receptor alpha. Brain Res 1561:11-22

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