This is a proposal for a pilot study to explore the feasibility of implementing an exercise program for Puerto Rican female patients who are breast cancer survivors. Participants will be randomly assigned to a gym-exercise group, a home-exercise group, or a non-exercise group. The proposed intervention will consist of an individualized, moderate intensity exercise program, offered for a 26-week period.
Specific aims for this study are: 1. to determine the potential benefits and complications of participating in the proposed exercise programs (gym-exercise and home-exercise programs), as opposed to standard care, and 2. to describe physical activity determinants and adherence to the exercise programs. Design: Multigroup Pretest-Posttest Control-Group. Methods: Ninety women, newly diagnosed with breast cancer, who have received surgical treatment, and have completed their adjuvant therapy, will be recruited by advertising to the general public. The women will be randomly assigned to a gym-exercise group, a home-exercise group, or a non-exercise group. The non-exercise group will receive standard care by continuing to use existing resources. The gym-exercise group will participate in a supervised, individualized aerobic and strengthening exercise program, requiring attendance to a gym three times per week, over 26 weeks. The home-exercise group will exercise at their homes and in their neighborhoods, participating in an individualized walking program and a resistance exercise program with elastic bands, over 26 weeks. Data will be collected on all participants, at baseline, at week 13 and at week 26. Outcome measurements will consist of functional evaluation, 12-minute walk test, upper extremity volume, handgrip strength, shoulder range of motion, weight, and quality of life.
|Rijpma, Sanna R; van der Velden, Maarten; González-Pons, Maria et al. (2016) Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites. Cell Microbiol 18:369-83|
|Padín-Irizarry, Vivian; Colón-Lorenzo, Emilee E; Vega-Rodríguez, Joel et al. (2016) Glutathione-deficient Plasmodium berghei parasites exhibit growth delay and nuclear DNA damage. Free Radic Biol Med 95:43-54|
|Jardón, Javier; Izquierdo, Natalio J; Renta, Jessica Y et al. (2016) Ocular Findings in Patients with the Hermansky-Pudlak Syndrome (Types 1 and 3). Ophthalmic Genet 37:89-94|
|Rivera-Peña, Bianca; Ruíz-Fullana, Francisco J; Vélez-Reyes, Germán L et al. (2016) HPV-16 infection modifies overall survival of Puerto Rican HNSCC patients. Infect Agent Cancer 11:47|
|Velásquez-Martínez, Maria C; Vázquez-Torres, Rafael; Rojas, Legier V et al. (2015) Alpha-1 adrenoreceptors modulate GABA release onto ventral tegmental area dopamine neurons. Neuropharmacology 88:110-21|
|Vega-Rodríguez, Joel; Pastrana-Mena, Rebecca; Crespo-Lladó, Keila N et al. (2015) Implications of Glutathione Levels in the Plasmodium berghei Response to Chloroquine and Artemisinin. PLoS One 10:e0128212|
|Zenón, Frances; Cantres-Rosario, Yisel; Adiga, Radhika et al. (2015) HIV-infected microglia mediate cathepsin B-induced neurotoxicity. J Neurovirol 21:544-58|
|Hodakoski, Cindy; Hopkins, Benjamin D; Barrows, Douglas et al. (2014) Regulation of PTEN inhibition by the pleckstrin homology domain of P-REX2 during insulin signaling and glucose homeostasis. Proc Natl Acad Sci U S A 111:155-60|
|Jezzini, Sami H; Reyes-Colón, Dalynés; Sosa, María A (2014) Characterization of a prawn OA/TA receptor in Xenopus oocytes suggests functional selectivity between octopamine and tyramine. PLoS One 9:e111314|
|Segarra, Annabell C; Torres-Díaz, Yvonne M; Silva, Richard D et al. (2014) Estrogen receptors mediate estradiol's effect on sensitization and CPP to cocaine in female rats: role of contextual cues. Horm Behav 65:77-87|
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