The general objective of the proposed University of Guam MBRS program is to provide opportunities for the faculty and talented minority students to conduct biomedically significant research utilizing the research facilities of the University of Guam. Four of the projects focus on marine biomedical research and will utilize the ecologically diverse tropical marine environment of Guam. The proposal includes five research projects submitted by regular principal investigators, a research project submitted by an associate investigator, and a well-structured enrichment component. Research projects include studies of genetics of reef fishes, genetics and reproductive biology of corals, genetics of learning and behavior in Drosophila, environmental microbiology of pathogenic microorganisms in nearshore marine habitats, and biophysical chemistry (2D nuclear magnetic resonance studies). Finally, an associate investigator project will focus on biomedically active natural products in coral-reef seaweeds and invertebrates. It is anticipated that through the proposed activities the student and faculty research environment will be enhanced. Faculty and students involved in research activities will interact with scientists in the mainland U.S. and will have the opportunity to learn new techniques and developments by participating in off-campus conferences and research activities as well as on-campus conferences and research activities as well as on-campus seminars, workshops, and informal discussions with visiting scientists. In the geographically isolated location of Guam, such experiences are especially valuable to the students when making decisions on postgraduate careers.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
2S06GM044796-04
Application #
3513672
Study Section
Minority Programs Review Committee (MPRC)
Project Start
1990-08-15
Project End
1997-08-14
Budget Start
1993-08-19
Budget End
1994-08-14
Support Year
4
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Guam
Department
Type
Organized Research Units
DUNS #
779908151
City
Mangilao
State
GU
Country
United States
Zip Code
96923
Steinert, Georg; Taylor, Michael W; Schupp, Peter J (2015) Diversity of Actinobacteria Associated with the Marine Ascidian Eudistoma toealensis. Mar Biotechnol (NY) 17:377-85
Wright, Anthony D; Schupp, Peter J; Schror, Jan-Philipp et al. (2012) Twilight zone sponges from Guam yield theonellin isocyanate and psammaplysins I and J. J Nat Prod 75:502-6
Rohde, Sven; Gochfeld, Deborah J; Ankisetty, Sridevi et al. (2012) Spatial variability in secondary metabolites of the indo-pacific sponge Stylissa massa. J Chem Ecol 38:463-75
Schmitt, Susanne; Tsai, Peter; Bell, James et al. (2012) Assessing the complex sponge microbiota: core, variable and species-specific bacterial communities in marine sponges. ISME J 6:564-76
Rohde, Sven; Schupp, Peter J (2011) Allocation of chemical and structural defenses in the sponge Melophlus sarasinorum. J Exp Mar Bio Ecol 399:76-83
Sharp, Koty H; Ritchie, Kim B; Schupp, Peter J et al. (2010) Bacterial acquisition in juveniles of several broadcast spawning coral species. PLoS One 5:e10898
Gaither, Michelle R; Rowan, Rob (2010) Zooxanthellar symbiosis in planula larvae of the coral Pocillopora damicornis. J Exp Mar Bio Ecol 386:45-53
Schupp, Peter J; Kohlert-Schupp, Claudia; Whitefield, Susanna et al. (2009) Cancer chemopreventive and anticancer evaluation of extracts and fractions from marine macro- and microorganisms collected from Twilight Zone waters around Guam. Nat Prod Commun 4:1717-28
Kitamura, Makoto; Schupp, Peter J; Nakano, Yoshikatsu et al. (2009) Luminaolide, a novel metamorphosis-enhancing macrodiolide for scleractinian coral larvae from crustose coralline algae. Tetrahedron Lett 50:6606
Manzo, Emiliano; Ciavatta, M Letizia; Melck, Dominique et al. (2009) Aromatic cyclic peroxides and related keto-compounds from the Plakortis sp. component of a sponge consortium. J Nat Prod 72:1547-51

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