Recent epidemiological results strongly suggest that a fourth epidemic of HIV infection is in process due to sex-for-drugs exchanges between adolescent crack users and intravenous drug users. A clear result of this new disease vector is that sexually active, economically disadvantaged adolescents are a new high risk group for being infected with the human immunodeficiency virus (HIV). The long range objective of the proposed study is to reduce substantially the spread of HIV infection among African American adolescents. An exhaustive list of family background factors and questions about community norms will be combined with social psychological factors related to HIV risk taking sexual behaviors. The structural variables will be derived from all of the explanations of the varied socioeconomic conditions among Blacks. The social psychological variables will be derived from the AIDS Risk Reduction Model (ARRM) and Social Cognitive Theory (SCT). A random probability sample of 425 east Oakland (Oakland, California) households with adolescents between the ages of 15 and 18 will be stratified by current socioeconomic status. One parent (guardian) and adolescent will be interviewed separately by Minority Biomedical Research Support students trained in survey research and interviewing. The adolescent sample will be divided by those who engage in low HIV risk behaviors and those who engage in high HIV risk behaviors. Analysis will identify both social psychological and structural pre-conditions to high and low HIV risk taking behaviors. This new information will suggest innovative approaches for modifying risk behaviors for HIV infection, thereby reducing the spread of the disease among target populations.

Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1993
Total Cost
Indirect Cost
Name
California State University Hayward
Department
Type
DUNS #
194044335
City
Hayward
State
CA
Country
United States
Zip Code
94542
Chu, Wally; Weerasekera, Akila; Kim, Chul-Hyun (2017) On the conformational stability of the smallest RNA kissing complexes maintained through two G·C base pairs. Biochem Biophys Res Commun 483:39-44
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Barnes, Donna B; Murphy, Sheigla (2009) Reproductive decisions for women with HIV: motherhood's role in envisioning a future. Qual Health Res 19:481-91
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Green, Lisa; Kim, Chul-Hyun; Bustamante, Carlos et al. (2008) Characterization of the mechanical unfolding of RNA pseudoknots. J Mol Biol 375:511-28
Hedrick, Michael S (2005) Development of respiratory rhythm generation in ectothermic vertebrates. Respir Physiol Neurobiol 149:29-41
Winmill, Rachel E; Chen, Anna K; Hedrick, Michael S (2005) Development of the respiratory response to hypoxia in the isolated brainstem of the bullfrog Rana catesbeiana. J Exp Biol 208:213-22
Hedrick, Michael S; Chen, Anna K; Jessop, Kristy L (2005) Nitric oxide changes its role as a modulator of respiratory motor activity during development in the bullfrog (Rana catesbeiana). Comp Biochem Physiol A Mol Integr Physiol 142:231-40
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Hedrick, Michael S; Winmill, Rachel E (2003) Excitatory and inhibitory effects of tricaine (MS-222) on fictive breathing in isolated bullfrog brain stem. Am J Physiol Regul Integr Comp Physiol 284:R405-12

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