This is a proposal for the establishment of a Minority Biomedical Research Support (MBRS) Program at Universidad Central del Caribe School of Medicine (UCCEM) in Puerto Rico. UCCEM was founded in 1976 as a private, non-profit medical school, since 1978 and 1979 it has been accredited by the Puerto Rico Council of Higher Education (CES) and by the Liaison Committee on Medical Education (LCME), respectively. In 1989, the CES gave full accreditation to a Graduate Program in the Basic Biomedical Sciences which offers M.A. and M.S. degrees. In 1992 memorandums of understanding (MOU's) were established with two neighboring institutions serving a large base of undergraduate minority students of PR, Universidad del Sagrado Corazon and Interamerican University. The accredited health- science (M.D.) and graduate (M.A., M.S.) programs of UCCEM plus the consortium arrangements with the undergraduate hispanic-servant universities cited above, provide the framework for implementing an MBRS program at UCCEM which embraces the mission of the national MBRS program of the NlGMS of """"""""seeking to provide expanded opportunities for underrepresented minorities to choose and participate in biomedical research careers and developing competitive biomedical research scientists who are also ethnic minorities"""""""". The specific goals of the MBRS Program at UCCEM are consonant to the goals of the National MBRS Program: l. to assist research scientists at UCCEM in the development, and continuity of their research capabilities and activities, 2. to expose undergraduate students from our affiliated institutions, Sacred Heart University and Interamerican University, to biomedical research activities, 3. to motivate minority undergraduates from our affiliated colleges and universities to pursue biomedical research careers, 4. to attract minority graduate degree students from these affiliated, and other non- affiliated, institutions to initiate studies in our Graduate Program and to pursue biomedical research careers, and 5. to attract minority graduate medical students at UCCEM to participate in scientific - biomedical research activities, and motivate them to pursue biomedical research careers in the clinical sciences. These objectives will be achieved by the MBRS Program at UCCEM via the following planned and proposed specific activities: l. faculty initiated, scientifically- meritorious, biomedically relevant research projects of subproject- Principal Investigators where the following UCCEM students can participate: graduate students, and medical students (summer time), and 2. implementation of the consortium with our affiliated institutions for the participation during the academic and summer periods of undergraduate/graduate students in the research projects of Principal Investigators at UCCEM.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
1S06GM050695-01
Application #
2188686
Study Section
Minority Programs Review Committee (MPRC)
Project Start
1994-08-01
Project End
1997-07-31
Budget Start
1994-08-01
Budget End
1995-07-31
Support Year
1
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Universidad Central Del Caribe
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Bayamon
State
PR
Country
United States
Zip Code
00960
Ferchmin, P A; Pérez, Dinely; Castro Alvarez, William et al. (2013) ?-Aminobutyric acid type A receptor inhibition triggers a nicotinic neuroprotective mechanism. J Neurosci Res 91:416-25
Jiménez-Rivera, Carlos A; Figueroa, Johnny; Vázquez-Torres, Rafael et al. (2012) Presynaptic inhibition of glutamate transmission by ?2 receptors in the VTA. Eur J Neurosci 35:1406-15
Arencibia-Albite, Francisco; Vázquez, Rafael; Velásquez-Martinez, María C et al. (2012) Cocaine sensitization inhibits the hyperpolarization-activated cation current Ih and reduces cell size in dopamine neurons of the ventral tegmental area. J Neurophysiol 107:2271-82
Martins, Antonio H; Alves, Janaina M; Perez, Dinely et al. (2012) Kinin-B2 receptor mediated neuroprotection after NMDA excitotoxicity is reversed in the presence of kinin-B1 receptor agonists. PLoS One 7:e30755
Schwarz, David; Bloom, Damaris; Castro, Rocío et al. (2011) Parthenolide Blocks Cocaine's Effect on Spontaneous Firing Activity of Dopaminergic Neurons in the Ventral Tegmental Area. Curr Neuropharmacol 9:17-20
Boukli, Nawal M; Saiyed, Zainulabedin M; Ricaurte, Martha et al. (2010) Implications of ER stress, the unfolded protein response, and pro- and anti-apoptotic protein fingerprints in human monocyte-derived dendritic cells treated with alcohol. Alcohol Clin Exp Res 34:2081-8
Inyushin, Mikhail; Kucheryavykh, Lilia Y; Kucheryavykh, Yuriy V et al. (2010) Potassium channel activity and glutamate uptake are impaired in astrocytes of seizure-susceptible DBA/2 mice. Epilepsia 51:1707-13
Martínez-Montemayor, Michelle M; Otero-Franqui, Elisa; Martinez, Joel et al. (2010) Individual and combined soy isoflavones exert differential effects on metastatic cancer progression. Clin Exp Metastasis 27:465-80
Inyushin, Mikhail; Kucheryaykh, Yuri; Kucheryavykh, Lilia et al. (2010) Membrane potential and pH-dependent accumulation of decynium-22 (1,1'-diethyl-2,2'-cyanine iodide) flourencence through OCT transporters in astrocytes. Bol Asoc Med P R 102:5-12
Acevedo-Torres, Karina; Berríos, Lexsy; Rosario, Nydia et al. (2009) Mitochondrial DNA damage is a hallmark of chemically induced and the R6/2 transgenic model of Huntington's disease. DNA Repair (Amst) 8:126-36

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