Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
3S06GM053933-06S3
Application #
6655872
Study Section
Minority Programs Review Committee (MPRC)
Project Start
2002-06-01
Project End
2003-05-31
Budget Start
Budget End
Support Year
6
Fiscal Year
2002
Total Cost
$263,865
Indirect Cost
City
Pomona
State
CA
Country
United States
Zip Code
91768
Dadgar, Saedeh; Floriano, Wely B (2015) Systematic discovery of molecular probes targeting multiple non-orthosteric and spatially distinct sites in the botulinum neurotoxin subtype A (BoNT/A). Mol Cell Probes 29:135-43
Dadgar, Saedeh; Ramjan, Zack; Floriano, Wely B (2013) Paclitaxel is an inhibitor and its boron dipyrromethene derivative is a fluorescent recognition agent for botulinum neurotoxin subtype A. J Med Chem 56:2791-803
Chew, Tina W; Jiang, Xinyin; Yan, Jian et al. (2011) Folate intake, MTHFR genotype, and sex modulate choline metabolism in mice. J Nutr 141:1475-81
Liang, M T C; Braun, W; Bassin, S L et al. (2011) Effect of high-impact aerobics and strength training on BMD in young women aged 20-35 years. Int J Sports Med 32:100-8
Yan, Jian; Wang, Wei; Gregory 3rd, Jesse F et al. (2011) MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline. Am J Clin Nutr 93:348-55
Shin, William; Yan, Jian; Abratte, Christian M et al. (2010) Choline intake exceeding current dietary recommendations preserves markers of cellular methylation in a genetic subgroup of folate-compromised men. J Nutr 140:975-80
Austin, Misa U; Liau, Wei-Siang; Balamurugan, Krishnaswamy et al. (2010) Knockout of the folate transporter folt-1 causes germline and somatic defects in C. elegans. BMC Dev Biol 10:46
Lewis, Samantha C; Dyal, Leslie A; Hilburn, Caroline F et al. (2009) Molecular evolution in Panagrolaimus nematodes: origins of parthenogenesis, hermaphroditism and the Antarctic species P. davidi. BMC Evol Biol 9:15
Caudill, Marie A; Dellschaft, Neele; Solis, Claudia et al. (2009) Choline intake, plasma riboflavin, and the phosphatidylethanolamine N-methyltransferase G5465A genotype predict plasma homocysteine in folate-deplete Mexican-American men with the methylenetetrahydrofolate reductase 677TT genotype. J Nutr 139:727-33
Ivanov, Alexandre; Nash-Barboza, Susan; Hinkis, Sabrina et al. (2009) Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted. J Am Diet Assoc 109:313-8

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