The SCORE Program at Cal Poly Pomona is designed to significantly improve the research capabilities of the University with the ultimate objectives of increasing the number of underrepresented minority biomedical scientists. To achieve these ends the program will fund high-quality research leading to peer-reviewed publications, strengthen the infrastructure for scientific research and lead to the submission of grant applications from alternate funding sources. The program includes fifteen sub-projects involving fifteen faculty with strong, demonstrable commitments to research, and graduate and undergraduate education. The program is interdisciplinary, involving faculty from four academic departments in two different colleges. The projects are diverse as well, covering topics ranging from human nutrition and health, to neurophysiology, cellular and molecular biology, and organic and biochemistry. In a recent survey of the undergraduate origins of recent doctorates in biological sciences, NSF ranked Cal Poly as one of the top 25 """"""""Masters Colleges and Universities."""""""" Under the leadership of a new president, J. Michael Ortiz, the University has placed high priority on: the enhancement of research and other scholarly activities; preparing students for life, leadership, and careers in a changing, multicultural world; and promoting academic excellence, educational equity, and diversity in the campus community. Policies and programs have been instituted that will benefit from and contribute to the success and impact of the SCORE program at Cal Poly, Pomona. The University has a very high level of commitment to the success of the SCORE program, committing to pay for one-half of all of the equipment needed for the proposed research and to match the release time purchased for the faculty. The departments participating in the SCORE proposal have been very effective at recruiting underrepresented students, with a higher percentage of underrepresented minority students and a more rapid growth rate than for the University as a whole.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Minority Biomedical Research Support - MBRS (S06)
Project #
Application #
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Singh, Shiva P
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
California State Polytechnic University Pomona
Schools of Arts and Sciences
United States
Zip Code
Dadgar, Saedeh; Floriano, Wely B (2015) Systematic discovery of molecular probes targeting multiple non-orthosteric and spatially distinct sites in the botulinum neurotoxin subtype A (BoNT/A). Mol Cell Probes 29:135-43
Dadgar, Saedeh; Ramjan, Zack; Floriano, Wely B (2013) Paclitaxel is an inhibitor and its boron dipyrromethene derivative is a fluorescent recognition agent for botulinum neurotoxin subtype A. J Med Chem 56:2791-803
Chew, Tina W; Jiang, Xinyin; Yan, Jian et al. (2011) Folate intake, MTHFR genotype, and sex modulate choline metabolism in mice. J Nutr 141:1475-81
Liang, M T C; Braun, W; Bassin, S L et al. (2011) Effect of high-impact aerobics and strength training on BMD in young women aged 20-35 years. Int J Sports Med 32:100-8
Yan, Jian; Wang, Wei; Gregory 3rd, Jesse F et al. (2011) MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline. Am J Clin Nutr 93:348-55
Shin, William; Yan, Jian; Abratte, Christian M et al. (2010) Choline intake exceeding current dietary recommendations preserves markers of cellular methylation in a genetic subgroup of folate-compromised men. J Nutr 140:975-80
Austin, Misa U; Liau, Wei-Siang; Balamurugan, Krishnaswamy et al. (2010) Knockout of the folate transporter folt-1 causes germline and somatic defects in C. elegans. BMC Dev Biol 10:46
Caudill, Marie A; Dellschaft, Neele; Solis, Claudia et al. (2009) Choline intake, plasma riboflavin, and the phosphatidylethanolamine N-methyltransferase G5465A genotype predict plasma homocysteine in folate-deplete Mexican-American men with the methylenetetrahydrofolate reductase 677TT genotype. J Nutr 139:727-33
Ivanov, Alexandre; Nash-Barboza, Susan; Hinkis, Sabrina et al. (2009) Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted. J Am Diet Assoc 109:313-8
Lee, Justine; Bernard, Steven; Liu, Xiao-Chuan (2009) Nanostructured Biomimetic Catalysts for Asymmetric Hydrogenation of Enamides using Molecular Imprinting Technology. React Funct Polym 69:650-654

Showing the most recent 10 out of 88 publications