The CSU San Marcos MBRS SCORE Program will advance the career development of seven faculty in the College of Arts and Sciences. Support is requested for research activities in the areas of clinical psychology and bilingual culturally-sensitive computerized depression screening, molecular biology of stress induced by viral infections, molecular biology of marine organism structure/function, marine anti-mycobacterial natural products studies, psychopharmacology of opiate actions, and environmental nitrogen flux as an early-warning indicator of pollution and human disease. The career development of faculty will be accompanied by involvement of students who will develop research knowledge and skills to prepare them for advanced biomedical research careers. Our program has seven major goals and measurable objectives including: Goal 1: Increase the publication activity of the participating SCORE faculty. By the end of the SCORE renewal grant the number of research publications submitted by the SCORE faculty will increase by 25%. Goal 2: Increase the grant proposal activity of the participating SCORE faculty. By the end of the SCORE renewal grant, the number of grant proposals submitted by the SCORE faculty will increase by 25%. Goal 3: Increase the number of professional presentations of the SCORE faculty. By the end of the SCORE renewal grant the number of professional presentations given by the SCORE faculty will increase by 25%. Goal 4: Enhance the racial and ethnic diversity of the faculty in the departments participating in the SCORE Program. By the end of the SCORE renewal grant at least one scientist from an underrepresented racial or ethnic group will be appointed as a tenure track faculty to each of these departments. Goal 5: Advance the academic rank of participating SCORE faculty. By the end of the SCORE renewal grant five participating SCORE faculty will be promoted to the rank of full professor. Goal 6: Increase student participation in biomedical research. By the end of the SCORE renewal grant the number of students participating in research in the laboratories of SCORE faculty will increase by 25%. Goal 7: Enhance the research environment of the university. By the end of the SCORE renewal grant, we expect to see a 25% improvement in evaluation scores for the campus research environment. Our evaluation plan provides formative and summative assessment for each project goal. The national SCORE Program's goals and the CSUSM strategic plan are in perfect alignment. The regional minority population growth, the campus commitment to diversity, the extensive experience of the proposed program director, the existing CSU San Marcos MBRS RISE, MARC-U*STAR and Bridges Programs, and the new science buildings equipped with modern scientific instruments and powerful instructional resources collectively make CSUSM an ideal location for a successful MBRS SCORE Program.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
5S06GM059833-06
Application #
6790024
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Singh, Shiva P
Project Start
1999-09-01
Project End
2007-08-31
Budget Start
2004-09-01
Budget End
2005-08-31
Support Year
6
Fiscal Year
2004
Total Cost
$894,349
Indirect Cost
Name
California State University San Marcos
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
176262681
City
San Marcos
State
CA
Country
United States
Zip Code
92078
Melkani, Girish C; Sielaff, Robin; Zardeneta, Gustavo et al. (2012) Interaction of oxidized chaperonin GroEL with an unfolded protein at low temperatures. Biosci Rep 32:299-303
Pasquini, Sarah C; Vourlitis, George L (2010) Post-fire primary production and plant community dynamics in chaparral stands exposed to varying levels of nitrogen deposition. J Arid Environ 74:310-314
Vourlitis, George L; Pasquini, Sarah C (2009) Experimental dry-season N deposition alters species composition in southern Californian mediterranean-type shrublands. Ecology 90:2183-9
Hizer, S E; Tamulis, W G; Robertson, L M et al. (2008) Evidence of multiple retrotransposons in two litopenaeid species. Anim Genet 39:363-73
Melkani, Girish C; Sielaff, Robin L; Zardeneta, Gustavo et al. (2008) Divalent cations stabilize GroEL under conditions of oxidative stress. Biochem Biophys Res Commun 368:625-30
Trujillo, Keith A; Zamora, Juan J; Warmoth, Kathleen P (2008) Increased response to ketamine following treatment at long intervals: implications for intermittent use. Biol Psychiatry 63:178-83
Mendez, Ian A; Trujillo, Keith A (2008) NMDA receptor antagonists inhibit opiate antinociceptive tolerance and locomotor sensitization in rats. Psychopharmacology (Berl) 196:497-509
Mothe, Bianca R; Stewart, Barbara S; Oseroff, Carla et al. (2007) Chronic lymphocytic choriomeningitis virus infection actively down-regulates CD4+ T cell responses directed against a broad range of epitopes. J Immunol 179:1058-67
Trujillo, Keith A; Castaneda, Edward; Martinez, Diana et al. (2006) Biological research on drug abuse and addiction in Hispanics: current status and future directions. Drug Alcohol Depend 84 Suppl 1:S17-28
Melkani, Girish C; Zardeneta, Gustavo; Mendoza, Jose A (2005) On the chaperonin activity of GroEL at heat-shock temperature. Int J Biochem Cell Biol 37:1375-85

Showing the most recent 10 out of 22 publications