Funds are requested for the purchase of a Leica TCS SP8X Confocal Microscope in order to replace an aging and degrading Zeiss 510 confocal microcope. The new Leica confocal microscope will serve as an integral resource to bolster and accelerate the research projects of an expanding interdepartmental group of NIH funded investigators in the Departments of Pharmacological Sciences, Pathology, and Medicine, all located in the same building complex in the School of Medicine of Stony Brook University. Importantly, the acquisition of the Leica SP8X will provide new technological advances over existing imaging technology available including a tunable white laser, vast improvements in sensitivity and scanning speeds, an increased field of view, superior tiling capabilities, and a state-of-the-art time lapse capabilities.
Funds are requested to acquire a Leica TCS SP8X Confocal Microscope in order to replace an aging confocal microcope with limited capabilities. The new Leica confocal microscope will serve as an essential resource to support and accelerate the research projects of an expanding interdepartmental group of NIH funded investigators at Stony Brook University. Importantly, the acquisition of the Leica SP8X will provide new technological capabilities over existing imaging technology enabling scientific advances that will contribute to a greater understanding of the cellular and molecular mechanisms underlying human disease.
| Shan, Xiwei; Tomlinson, Lyl; Yang, Qian et al. (2018) Distinct Requirements for Extracellular and Intracellular MMP12 in the Development of the Adult V-SVZ Neural Stem Cell Niche. Stem Cell Reports 10:984-999 |
| Tomlinson, Lyl; Huang, Po Hsuan; Colognato, Holly (2018) Prefrontal cortex NG2 glia undergo a developmental switch in their responsiveness to exercise. Dev Neurobiol 78:687-700 |
