We propose the acquisition of a console capable of both magnetic resonance spectroscopy and imaging, using an existing magnet, for in vivo studies. The instrument will be used for studies of heart, brain, gut, and tumors in small animals (principally rats) as well as for development of new magnetic resonance methodologies.
| Litt, L; Xu, Y; Cohen, Y et al. (1993) Nonmagnetic hyperbaric chamber for in vivo NMR spectroscopy studies of small animals. Magn Reson Med 29:812-6 |
| Xu, Y; Cohen, Y; Litt, L et al. (1991) Tolerance of low cerebral intracellular pH in rats during hyperbaric hypercapnia. Stroke 22:1303-8 |
| Litt, L; Lockhart, S; Cohen, Y et al. (1991) In vivo 19F nuclear magnetic resonance brain studies of halothane, isoflurane, and desflurane. Rapid elimination and no abundant saturable binding. Ann N Y Acad Sci 625:707-24 |
| Cohen, Y; Chang, L H; Litt, L et al. (1990) Stability of brain intracellular lactate and 31P-metabolite levels at reduced intracellular pH during prolonged hypercapnia in rats. J Cereb Blood Flow Metab 10:277-84 |
