Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biomedical Research Support Shared Instrumentation Grants (S10)
Project #
1S10RR011434-01
Application #
2286971
Study Section
Special Emphasis Panel (ZRG7-SSS-X (56))
Project Start
1996-05-15
Project End
1997-05-14
Budget Start
1996-05-15
Budget End
1997-05-14
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Ohio State University
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Liñán-Rico, A; Wunderlich, J E; Enneking, J T et al. (2015) Neuropharmacology of purinergic receptors in human submucous plexus: Involvement of P2X?, P2X?, P2X? channels, P2Y and A? metabotropic receptors in neurotransmission. Neuropharmacology 95:83-99
Ochoa-Cortes, Fernando; Liñán-Rico, Andromeda; Jacobson, Kenneth A et al. (2014) Potential for developing purinergic drugs for gastrointestinal diseases. Inflamm Bowel Dis 20:1259-87
Liñán-Rico, Andrómeda; Wunderlich, Jacqueline E; Grants, Iveta S et al. (2013) Purinergic autocrine regulation of mechanosensitivity and serotonin release in a human EC model: ATP-gated P2X3 channels in EC are downregulated in ulcerative colitis. Inflamm Bowel Dis 19:2366-79
Ren, Tianhua; Grants, Iveta; Alhaj, Mazin et al. (2011) Impact of disrupting adenosine A? receptors (A??/? AR) on colonic motility or progression of colitis in the mouse. Inflamm Bowel Dis 17:1698-713
Bozarov, Andrey; Wang, Yu-Zhong; Yu, Jun Ge et al. (2009) Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine. Am J Physiol Gastrointest Liver Physiol 297:G1147-62
Chen, Zhixiong; Suntres, Zach; Palmer, Jeffrey et al. (2007) Cyclic AMP signaling contributes to neural plasticity and hyperexcitability in AH sensory neurons following intestinal Trichinella spiralis-induced inflammation. Int J Parasitol 37:743-61
Cooke, Helen J; Xue, Jianjing; Yu, Jun Ge et al. (2004) Mechanical stimulation releases nucleotides that activate P2Y1 receptors to trigger neural reflex chloride secretion in guinea pig distal colon. J Comp Neurol 469:1-15
Christofi, Fievos L; Wunderlich, Jacqueline; Yu, Jun Ge et al. (2004) Mechanically evoked reflex electrogenic chloride secretion in rat distal colon is triggered by endogenous nucleotides acting at P2Y1, P2Y2, and P2Y4 receptors. J Comp Neurol 469:16-36
Cooke, Helen J; Wunderlich, Jacqueline; Christofi, Fievos L (2003) ""The force be with you"": ATP in gut mechanosensory transduction. News Physiol Sci 18:43-9
Christofi, F L (2001) Unlocking mysteries of gut sensory transmission: is adenosine the key? News Physiol Sci 16:201-7

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