Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biomedical Research Support Shared Instrumentation Grants (S10)
Project #
1S10RR012023-01
Application #
2040671
Study Section
Special Emphasis Panel (ZRG3-SSS-6 (15))
Project Start
1997-05-15
Project End
1998-05-14
Budget Start
1997-05-15
Budget End
1998-05-14
Support Year
1
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Florida
Department
Miscellaneous
Type
Schools of Pharmacy
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Prokai, Laszlo; Nguyen, Vien; Szarka, Szabolcs et al. (2015) The prodrug DHED selectively delivers 17?-estradiol to the brain for treating estrogen-responsive disorders. Sci Transl Med 7:297ra113
Prokai-Tatrai, Katalin; Prokai, Laszlo (2009) Prodrugs of thyrotropin-releasing hormone and related peptides as central nervous system agents. Molecules 14:633-54
Prokai-Tatrai, Katalin; Perjesi, Pal; Rivera-Portalatin, Nilka M et al. (2008) Mechanistic investigations on the antioxidant action of a neuroprotective estrogen derivative. Steroids 73:280-8
Rivera-Portalatin, Nilka M; Vera-Serrano, Jose L; Prokai-Tatrai, Katalin et al. (2007) Comparison of estrogen-derived ortho-quinone and para-quinol concerning induction of oxidative stress. J Steroid Biochem Mol Biol 105:71-5
Prokai, Laszlo; Zharikova, Alevtina D; Stevens Jr, Stanley M (2005) Effect of chronic morphine exposure on the synaptic plasma-membrane subproteome of rats: a quantitative protein profiling study based on isotope-coded affinity tags and liquid chromatography/mass spectrometry. J Mass Spectrom 40:169-75
Prokai, Laszlo; Prokai-Tatrai, Katalin; Perjesi, Pal et al. (2003) Quinol-based metabolic cycle for estrogens in rat liver microsomes. Drug Metab Dispos 31:701-4
Stevens Jr, Stanley M; Zharikova, Alevtina D; Prokai, Laszlo (2003) Proteomic analysis of the synaptic plasma membrane fraction isolated from rat forebrain. Brain Res Mol Brain Res 117:116-28
Prokai, Laszlo; Prokai-Tatrai, Katalin; Perjesi, Pal et al. (2003) Quinol-based cyclic antioxidant mechanism in estrogen neuroprotection. Proc Natl Acad Sci U S A 100:11741-6
Zharikova, Alevtina; Zharikov, Sergey; Block, Edward R et al. (2002) Metabolism of dynorphins by peptidases of pulmonary artery endothelial cells. Endothelium 9:37-44
Prokai, L; Zharikova, A; Janaky, T et al. (2001) Integration of mass spectrometry into early-phase discovery and development of central nervous system agents. J Mass Spectrom 36:1211-9

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