This is a postdoctoral training program designed to produce well trained independent researchers in the area of alcohol abuse and alcoholism. The program has three broad areas of training, pharmacology, behavior and genetics. These areas are covered by the large and well funded training faculty in all of these areas. There are four schools, two Alcohol Research Centers and one Institute within the University of Colorado involved: School of Medicine with the Departments of Pharmacology and Psychiatry, School of Dentistry, the School of Pharmacy and the College of Arts and Sciences with the Department of Psychology, the Institute for Behavioral Genetics the NIAAA Alcohol Research Center and the VA Alcohol Research Center. Trainees with a doctoral degree are recruited from a broad range of disciplines; neurochemistry, neurophysiology, biochemistry, pharmacy, .pharmacology, psychology, medicine, genetics, molecular biology, and :molecular genetics in addition to others. The trainees become familiar with the approaches of behavioral pharmacogenetics as a discipline and its various components in the solving of problems related to alcohol actions and alcoholism. Laboratories cover the topics from human epidemiological and genetic studies to molecular cloning of genes from animals. Pharmacological, genetic and/or behavioral tools are in use in the majority of laboratories. Research in one of these laboratories and contact with the rest of faculty through a regular seminar series, Alcohol Research Center retreats and various courses complete the training environment.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Institutional National Research Service Award (T32)
Project #
5T32AA007464-23
Application #
6027156
Study Section
Special Emphasis Panel (ZAA1-DD (02))
Project Start
1987-01-01
Project End
2002-02-28
Budget Start
1999-03-01
Budget End
2000-02-29
Support Year
23
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Pharmacology
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Wills, Amanda G; Evans, Luke M; Hopfer, Christian (2017) Phenotypic and Genetic Relationship Between BMI and Drinking in a Sample of UK Adults. Behav Genet 47:290-297
Sinnen, Brooke L; Bowen, Aaron B; Forte, Jeffrey S et al. (2017) Optogenetic Control of Synaptic Composition and Function. Neuron 93:646-660.e5
Powers, Matthew S; Smith, Phillip H; McKee, Sherry A et al. (2017) From sexless to sexy: Why it is time for human genetics to consider and report analyses of sex. Biol Sex Differ 8:15
Tencer, Adam H; Cox, Khan L; Di, Luo et al. (2017) Covalent Modifications of Histone H3K9 Promote Binding of CHD3. Cell Rep 21:455-466
Tencer, Adam H; Gatchalian, Jovylyn; Klein, Brianna J et al. (2017) A Unique pH-Dependent Recognition of Methylated Histone H3K4 by PPS and DIDO. Structure 25:1530-1539.e3
Lind, Kimberly E; Gutierrez, Eric J; Yamamoto, Dorothy J et al. (2017) Sex disparities in substance abuse research: Evaluating 23 years of structural neuroimaging studies. Drug Alcohol Depend 173:92-98
Andrews, Forest H; Gatchalian, Jovylyn; Krajewski, Krzysztof et al. (2016) Regulation of Methyllysine Readers through Phosphorylation. ACS Chem Biol 11:547-53
Andrews, Forest H; Strahl, Brian D; Kutateladze, Tatiana G (2016) Insights into newly discovered marks and readers of epigenetic information. Nat Chem Biol 12:662-8
Klein, Brianna J; Muthurajan, Uma M; Lalonde, Marie-Eve et al. (2016) Bivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation. Nucleic Acids Res 44:472-84
Andrews, Forest H; Tong, Qiong; Sullivan, Kelly D et al. (2016) Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase. Cell Rep 16:3195-3207

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