This resubmission application is for continued support of the Multidisciplinary Alcoholism Research Training program at the University of Michigan, now in its 23rd year of funding from the National Institute on Alcohol Abuse and Alcoholism. Since its initial funding in 1990, the program has trained 56 research fellows, including 46 postdoctoral fellows, of whom 10 are physician scientists, and 12 predoctoral fellows. In the next five years, the program will build on its previous success by concentrating on training four postdoctoral fellows, including one physician, per year. The University of Michigan Addiction Research Center (UMARC) in the Department of Psychiatry's Substance Abuse Section houses the training program, and has 22 faculty addiction researchers working on more than 35 projects, including over $4.2M in annual funding from NIAAA. UMARC research is focused in six areas: (1) Developmental Psychopathology and Genetics; (2) Prevention and Early Intervention; (3) Health Services Research; (4) Brain Function and Neurophysiology; (5) Treatment; and (6) Translational Research. UMARC has extensive collaborative relationships pertaining to alcohol-related research throughout the University, including faculty in the Schools of Public Health, Social Work, and Nursing, as well as other medical school departments such as Emergency Medicine, Pharmacology, and Genetics, all of whom may serve as mentors and enrich the multidisciplinary focus of training. In addition, UMARC supports a 12-year-old NIH/Fogarty International Center collaborative research training program for the improvement of addiction research infrastructure in Central and Eastern Europe, especially Poland and Ukraine. A clinical addiction psychiatry fellowship program and addiction treatment clinic, which are co-located in the same facility as the NIAAA research training program, provide an opportunity for clinical exposure, observation, and subject recruitment for translational research fellows. An intense mentored research relationship, coupled with a graded set of research and didactic experiences, manuscript and grant writing, and clinical exposure for translational researchers, are the core elements of training. This revision addresses key issues that will both continue and increase the high quality and post-training productivity of program graduates. The PI and other key mentors have a long history of NIAAA-funded research, combined with other NIH funding, and mentorship that provide important opportunities for trainees to develop productive alcohol research careers.

Public Health Relevance

Each year, problems related to alcohol consumption, abuse, and dependence cause 79,000 deaths and cost approximately $223.5 billion in the United States. Scientific research into the causes and prevention of alcohol-related problems across the lifespan, as well as treatment advances for individuals diagnosed with alcohol dependence is urgently needed to address these public health concerns. The purpose of this training grant application is to train and equip the next generation of scientific researchers who are interested in understanding and ameliorating the costs, causes, and consequences of alcohol-related problems.

National Institute of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Special Emphasis Panel (ZAA1)
Program Officer
Bechtholt, Anita
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Michigan Ann Arbor
Schools of Medicine
Ann Arbor
United States
Zip Code
Davis, Alan K; Arterberry, Brooke J; Bonar, Erin E et al. (2018) Predictors of positive drinking outcomes among youth receiving an alcohol brief intervention in the emergency department. Drug Alcohol Depend 188:102-108
Gard, Arianna M; Waller, Rebecca; Swartz, Johnna R et al. (2018) Amygdala functional connectivity during socioemotional processing prospectively predicts increases in internalizing symptoms in a sample of low-income, urban, young men. Neuroimage 178:562-573
Davis, Alan K; Nickelsen, Tetiana; Zucker, Robert A et al. (2018) Acceptability of nonabstinent treatment outcome goals among addiction treatment providers in Ukraine. Psychol Addict Behav 32:485-495
Waller, Rebecca; Hyde, Luke W (2018) Callous-unemotional behaviors in early childhood: the development of empathy and prosociality gone awry. Curr Opin Psychol 20:11-16
Waller, Rebecca; McCabe, Hannah K; Dotterer, Hailey L et al. (2018) Unique and Interactive Associations Between Maltreatment and Complex Emotion Recognition Deficits and Psychopathic Traits in an Undergraduate Sample. J Pers Disord 32:543-561
Fava, Nicole M; Trucco, Elisa M; Martz, Meghan E et al. (2018) Childhood adversity, externalizing behavior, and substance use in adolescence: Mediating effects of anterior cingulate cortex activation during inhibitory errors. Dev Psychopathol :1-12
Davis, Alan K; Lin, Lewei A; Ilgen, Mark A et al. (2018) Recent cannabis use among Veterans in the United States: Results from a national sample. Addict Behav 76:223-228
Davis, Alan K; Arterberry, Brooke J; Bonar, Erin E et al. (2018) Why do young people consume marijuana? Extending motivational theory via the Dualistic Model of Passion. Transl Issues Psychol Sci 4:54-64
Martz, Meghan E; Zucker, Robert A; Schulenberg, John E et al. (2018) Psychosocial and neural indicators of resilience among youth with a family history of substance use disorder. Drug Alcohol Depend 185:198-206
Martz, Meghan E; Schulenberg, John E; Patrick, Megan E (2018) Passing on Pot: High School Seniors' Reasons for Not Using Marijuana as Predictors of Future Use. J Stud Alcohol Drugs 79:761-769

Showing the most recent 10 out of 135 publications