The objective of this training program is to develop a cadre of physician-scientists with expertise in geriatric clinical epidemiology, capable of addressing the complex and multidimensional health problems of older persons. We will accomplish this objective by providing physicians already well trained in geriatrics and/or subspecialties with age-related relevance with 2 - 3 years of research training. The geriatric clinical epidemiology trainees will develop skills in each of seven essential areas: 1) formulation of significant and focused research questions; 2) design of observational and experimental studies; 3) techniques for successful execution of specific study designs; 4) critical analysis of the scientific literature; 5) interpretation of findings; 6) verbal and written communication of scientific methods and findings; and 7) development and implementation of strategies for research support. These skills will be developed through a training experience that includes both didactic and experiential components. The core didactic curriculum is a 1-year long course, Quantitative Clinical Epidemiology, which includes epidemiologic and research methods, biostatistics, data processing, and health policy. Advanced courses, provided through the new Investigative Medicine Program and the School of Public Health, include clinical investigation, longitudinal data analysis, and ethics in research. Trainees will have the option of obtaining an MPH or a PhD. The central component of the research training program is a supervised research experience under the guidance of a geriatric faculty mentor. There is a broad array of interdisciplinary and ongoing research projects upon which trainees can draw for the experiential component of their research training. The unique strengths of the proposed training program include a distinguished history of geriatric clinical epidemiology research; the breadth and depth of available mentors and research expertise; an outstanding didactic research curriculum; availability of a broad spectrum of research experience opportunities and an excellent research infrastructure; an outstanding pool of trainee candidates; and a program director widely recognized for developing successful geriatric clinical investigators.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Institutional National Research Service Award (T32)
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National Institute on Aging Initial Review Group (NIA)
Program Officer
Yancik, Rosemary
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Yale University
Internal Medicine/Medicine
Schools of Medicine
New Haven
United States
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Farhadian, Shelli; Jalbert, Emilie; Deng, Yanhong et al. (2018) HIV and Age Do Not Synergistically Affect Age-Related T-Cell Markers. J Acquir Immune Defic Syndr 77:337-344
Monin, Joan K; Xu, Annie; Mitchell, Hannah-Rose et al. (2018) Recalling support provision decreases distress and anger in response to partner suffering. Aging Ment Health 22:587-594
Rhee, Taeho Greg; Rosenheck, Robert A (2018) Does improvement in symptoms and quality of life in chronic schizophrenia reduce family caregiver Burden? Psychiatry Res 271:402-404
Riffin, Catherine; Van Ness, Peter H; Wolff, Jennifer L et al. (2018) Multifactorial Examination of Caregiver Burden in a National Sample of Family and Unpaid Caregivers. J Am Geriatr Soc :
Rhee, Taeho Greg (2018) Continuing versus New Antidepressant Use in Older Adults: US Prescribing Trends from 2006 to 2015. Eur Geriatr Med 9:551-555
Cohen, Andrew B; Trentalange, Mark; Benjamin, Andrea Z et al. (2018) Characteristics of Patients With Professional Guardians in the Department of Veterans Affairs Health Care System. JAMA Intern Med :
Miner, Brienne; Gill, Thomas M; Yaggi, H Klar et al. (2018) Insomnia in Community-Living Persons with Advanced Age. J Am Geriatr Soc 66:1592-1597
Rhee, Taeho Greg; Westberg, Sarah M; Harris, Ila M (2018) Use of Complementary and Alternative Medicine in Older Adults With Diabetes. Diabetes Care 41:e95-e96
Farhadian, Shelli F; Mehta, Sameet S; Zografou, Chrysoula et al. (2018) Single-cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid during virologically suppressed HIV. JCI Insight 3:
Ouellet, Gregory M; Ouellet, Jennifer A; Tinetti, Mary E (2018) Principle of rational prescribing and deprescribing in older adults with multiple chronic conditions. Ther Adv Drug Saf 9:639-652

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