This is the third competing renewal of the Yale Training Program in Geriatric Clinical Epidemiology and Aging- Related Research. The objective of the Yale Program is to develop a cadre of physician scientists and PhD investigators with expertise in geriatric clinical epidemiology and/or translational aging research who will be equipped to address the myriad of unanswered questions concerning the diagnosis, etiology, treatment, prevention, and prognosis of the health problems experienced by the ever-increasing number of older persons. We will accomplish this objective by providing highly qualified physicians, who are already well trained in geriatrics and/or subspecialties with age-related relevance, and outstanding PhD-trained investigators with 2 to 3 years of rigorous research training. Our trainees will develop skills in each of 10 essential areas: 1) formulation of significant and focused research questions and hypotheses; 2) design of observational, mechanistic and/or experimental studies to address focused research questions; 3) techniques for successful execution of specific study designs; 4) project and/or laboratory management; 5) critical analysis of the scientific literature, including research methods and data quality; 6) interpretation of findings; 7) oral and written communication of scientific methods and findings; 8) development and implementation of strategies for research support; 9) research team approaches and leadership; and 10) budget management. These skills will be developed through a training experience that includes both didactic and experiential components. The didactic curriculum includes courses offered through the Clinical Scholars Program, Investigative Medicine Program and School of Public Health, coupled with several high quality aging-specific training venues at Yale and offsite. The central component of the Yale Program is a mentored research experience, which includes structured meetings with Program Faculty in geriatrics/gerontology and at least one supervised research project tailored to the trainee's experiences and interests, with the goal of producing one or more first- authored, peer-reviewed publications and a grant application to support further research. The Yale Program has successfully recruited and retained a full complement of outstanding trainees during each of the first 14 years, and has successfully placed many of its graduates in tenure-track, research-intensive positions at top- tier academic institutions. For the next five years, we request continued funding for four postdoctoral positions.

Public Health Relevance

The objective of the Yale Training Program in Geriatric Clinical Epidemiology and Aging-Related Research is to develop a cadre of physician scientists and PhD investigators with expertise in geriatric clinical epidemiology and/or translational aging research who will be equipped to address the myriad of unanswered questions concerning the diagnosis, etiology, treatment, management, prevention, and prognosis of the health problems experienced by the ever-increasing number of older persons.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Institutional National Research Service Award (T32)
Project #
5T32AG019134-17
Application #
9265368
Study Section
Special Emphasis Panel (ZAG1-ZIJ-1 (J1))
Program Officer
Eldadah, Basil A
Project Start
2001-05-01
Project End
2021-04-30
Budget Start
2017-05-01
Budget End
2018-04-30
Support Year
17
Fiscal Year
2017
Total Cost
$326,868
Indirect Cost
$21,012
Name
Yale University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Rhee, Taeho Greg (2018) Continuing versus New Antidepressant Use in Older Adults: US Prescribing Trends from 2006 to 2015. Eur Geriatr Med 9:551-555
Cohen, Andrew B; Trentalange, Mark; Benjamin, Andrea Z et al. (2018) Characteristics of Patients With Professional Guardians in the Department of Veterans Affairs Health Care System. JAMA Intern Med :
Miner, Brienne; Gill, Thomas M; Yaggi, H Klar et al. (2018) Insomnia in Community-Living Persons with Advanced Age. J Am Geriatr Soc 66:1592-1597
Rhee, Taeho Greg; Westberg, Sarah M; Harris, Ila M (2018) Use of Complementary and Alternative Medicine in Older Adults With Diabetes. Diabetes Care 41:e95-e96
Farhadian, Shelli F; Mehta, Sameet S; Zografou, Chrysoula et al. (2018) Single-cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid during virologically suppressed HIV. JCI Insight 3:
Ouellet, Gregory M; Ouellet, Jennifer A; Tinetti, Mary E (2018) Principle of rational prescribing and deprescribing in older adults with multiple chronic conditions. Ther Adv Drug Saf 9:639-652
Rhee, Taeho Greg; Capistrant, Benjamin D; Schommer, Jon C et al. (2018) Effects of the 2009 USPSTF Depression Screening Recommendation on Diagnosing and Treating Mental Health Conditions in Older Adults: A Difference-in-Differences Analysis. J Manag Care Spec Pharm 24:769-776
Rhee, Taeho Greg; Mohamed, Somaia; Rosenheck, Robert A (2018) Antipsychotic Prescriptions Among Adults With Major Depressive Disorder in Office-Based Outpatient Settings: National Trends From 2006 to 2015. J Clin Psychiatry 79:
Hajduk, Alexandra M; Hyde, Jacquelyn E; Waring, Molly E et al. (2018) Practical Care Support During the Early Recovery Period After Acute Coronary Syndrome. J Appl Gerontol 37:881-903
Makris, Una E; Weinreich, Mark A; Fraenkel, Liana et al. (2018) Restricting Back Pain and Subsequent Disability in Activities of Daily Living Among Community-Living Older Adults. J Aging Health 30:1482-1494

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