The primary purpose of this program has been and will continue to be the training of young physicians with strong academic potential in such a way that they will qualify for full-time medical school faculty positions as allergists and clinical immunologists. Upon completion of his or her training, such a physician should be capable not only of directing research in allergy and immunology but of teaching other physicians the fundamental concepts and clinical expertise necessary for optimum care of patients with allergic and immunologic disorders. The program will place strong emphasis on research training and acquisition of basic immunologic knowledge. These goals will be accomplished through: 1) formal courses in basic immunology and other related disciplines, 2) precepted research training in immunology and molecular biology, and 3) limited clinical exposure to a variety of allergic and immunologic problems so that experience can be gained in the evaluation of patients with these disorders. The training of these fellows in allergy and clinical immunology will take place at Duke University in the Departments of Pediatrics, Medicine, Pathology and Immunology and at the University of North Carolina ? Chapel Hill in the Departments of Pediatrics, Pharmacology, Medicine. The program will be conducted by twenty-five full-time faculty members. The proposed program has a good record of accomplishment over the past 30 years. This application requests support for six trainees each year. The research training will center on research currently ongoing in the various faculty members' laboratories or in the laboratories of other collaborating basic scientists within the Medical Center and the University of North Carolina ? Chapel Hill. Fulfillment of the program's objective would directly or indirectly serve to meet two urgent medical needs: 1) the need for more full-time researchers and teachers of allergy and clinical immunology in medical schools throughout the country and 2) the need for more physicians trained in the specific care of patients with allergic and immunologic disorders.
To develop innovative pediatric physician-scientists trained in the latest methods of laboratory and clinical research and fully prepared to pursue independent academic careers investigating critical issues in allergy and clinical immunology. These trainees will become key mentors to future pediatric physician-scientists.
| Iweala, Onyinye I; Copenhaver, Christopher; Wu, Eveline Y et al. (2018) Hydroxychloroquine as a steroid-sparing agent in an infant with chronic urticaria. Ann Allergy Asthma Immunol 120:102-104 |
| Sood, Amika K; Funkhouser, William; Handly, Brian et al. (2018) Granulomatous-Lymphocytic Interstitial Lung Disease in 22q11.2 Deletion Syndrome: a Case Report and Literature Review. Curr Allergy Asthma Rep 18:14 |
| LoVerde, Daniel; Iweala, Onyinye I; Eginli, Ariana et al. (2018) Anaphylaxis. Chest 153:528-543 |
| Sood, Amika K; Kesic, Matthew J; Hernandez, Michelle L (2018) Electronic cigarettes: One size does not fit all. J Allergy Clin Immunol 141:1973-1982 |
| Lugogo, Njira; Green, Cynthia L; Agada, Noah et al. (2018) Obesity's effect on asthma extends to diagnostic criteria. J Allergy Clin Immunol 141:1096-1104 |
| Hamad, Ahmad; Iweala, Onyinye I; Henderson, Cory et al. (2018) Recurrent anaphylaxis during cardiac catheterization due to ethylene oxide. J Allergy Clin Immunol Pract 6:2148-2150 |
| Ro, Teresa; Sood, Amika; Kelly, Kevin J et al. (2018) What Is the Cause of the Chronic Erythematous Scaling Plaques on This 22-Month-Old Girl and Her Family? Clin Pediatr (Phila) 57:874-878 |
| Iweala, Onyinye I; Choudhary, Shailesh K; Commins, Scott P (2018) Food Allergy. Curr Gastroenterol Rep 20:17 |
| Vickery, Brian P; Berglund, Jelena P; Burk, Caitlin M et al. (2017) Early oral immunotherapy in peanut-allergic preschool children is safe and highly effective. J Allergy Clin Immunol 139:173-181.e8 |
| Wu, E Y; Schanberg, L E; Wershba, E C et al. (2017) Lenalidomide for refractory cutaneous manifestations of pediatric systemic lupus erythematosus. Lupus 26:646-649 |
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