This program provides background and training in the areas of molecular and cellular immunology, molecular and biochemical microbiology, and eukaryotic and procaryotic molecular genetics. The goal is to develop high competent investigators capable of performing and eventually directing research in basic modern microbiology and immunology. Trainees are exposed to a variety of perspectives, ideas, and methodologies which can be utilized in their dissertation research and careers as investigators. Rigorous research training is provided in studies of eukaryotic and prokaryotic systems using combinations of molecular, biochemical, genetic, and cellular approaches. While relationships to human disease are emphasized, trainees receive experience in the most modern molecular and biochemical technologies. Research disciplines include molecular and cellular immunology, microbial biochemistry, molecular genetics, mycology, virology, bacteriology, and cell biology. Predoctoral trainees complete a rigorous series of graduate courses providing them with a thorough background in microbiology and immunology. First year students complete courses in the molecular basis of pathogenic microbiology, molecular and cellular immunology, and microbial genetics and physiology. This is followed by advanced elective courses, several series of seminars by outside speakers and faculty, and by journal club participation. Trainees are required to complete rotations in three laboratories prior to the selection of a permanent advisor and a dissertation research topic. Applicants must have a bachelor's degree from an accredited institution, and a solid background in biological and chemical sciences. Only full time students are accepted. Postdoctoral trainees are often offered the opportunity to work in collaboration with more than one preceptor as a part of this Training Program. The postdoctoral trainee is encouraged to utilize resources available throughout the Health Sciences Center. Postdoctoral trainees must have received a Ph.D. or M.D. degree, and past productivity as assessed by publication record is used, at least in part, as the basis for evaluating applicants.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI007101-25
Application #
6631689
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Mcsweegan, Edward
Project Start
1978-09-01
Project End
2004-06-30
Budget Start
2003-06-01
Budget End
2004-06-30
Support Year
25
Fiscal Year
2003
Total Cost
$215,794
Indirect Cost
Name
Temple University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
057123192
City
Philadelphia
State
PA
Country
United States
Zip Code
19122
Kocieda, Virginia P; Adhikary, Sabina; Emig, Frances et al. (2012) Prostaglandin E2-induced IL-23p19 subunit is regulated by cAMP-responsive element-binding protein and C/AATT enhancer-binding protein ? in bone marrow-derived dendritic cells. J Biol Chem 287:36922-35
Regan, Genevieve; Itaya, Mitsuhiro; Piggot, Patrick J (2012) Coupling of ýýG activation to completion of engulfment during sporulation of Bacillus subtilis survives large perturbations to DNA translocation and replication. J Bacteriol 194:6264-71
Chan, Marion M; Evans, Kyle W; Moore, Andrea R et al. (2010) Peroxisome proliferator-activated receptor (PPAR): balance for survival in parasitic infections. J Biomed Biotechnol 2010:828951
Happel, Christine; Steele, Amber D; Finley, Matthew J et al. (2008) DAMGO-induced expression of chemokines and chemokine receptors: the role of TGF-beta1. J Leukoc Biol 83:956-63
Monos, Dimitri S; Pappas, John; Magira, Eleni E et al. (2005) Identification of HLA-DQalpha and -DRbeta residues associated with susceptibility and protection to epithelial ovarian cancer. Hum Immunol 66:554-62
Hilbert, David W; Chary, Vasant K; Piggot, Patrick J (2004) Contrasting effects of sigmaE on compartmentalization of sigmaF activity during sporulation of Bacillus subtilis. J Bacteriol 186:1983-90
Hilbert, David W; Piggot, Patrick J (2004) Compartmentalization of gene expression during Bacillus subtilis spore formation. Microbiol Mol Biol Rev 68:234-62
Sakkas, Lazaros I; Koussidis, George; Avgerinos, Efthimios et al. (2004) Decreased expression of the CD3zeta chain in T cells infiltrating the synovial membrane of patients with osteoarthritis. Clin Diagn Lab Immunol 11:195-202
Oleszak, Emilia L; Chang, J Robert; Friedman, Herman et al. (2004) Theiler's virus infection: a model for multiple sclerosis. Clin Microbiol Rev 17:174-207
Hilbert, David W; Piggot, Patrick J (2003) Novel spoIIE mutation that causes uncompartmentalized sigmaF activation in Bacillus subtilis. J Bacteriol 185:1590-8

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