Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
2T32AI007272-06
Application #
3531064
Study Section
Acquired Immunodeficiency Syndrome Research Review Committee (AIDS)
Project Start
1989-09-01
Project End
1994-08-31
Budget Start
1989-09-01
Budget End
1990-08-31
Support Year
6
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Type
Schools of Medicine
DUNS #
660735098
City
Worcester
State
MA
Country
United States
Zip Code
01655
Colbert, Jeff D; Farfán-Arribas, Diego J; Rock, Kenneth L (2013) Substrate-induced protein stabilization reveals a predominant contribution from mature proteins to peptides presented on MHC class I. J Immunol 191:5410-9
Oestreich, Kenneth J; Weinmann, Amy S (2012) T-bet employs diverse regulatory mechanisms to repress transcription. Trends Immunol 33:78-83
Meriin, Anatoli B; Mense, Martin; Colbert, Jeff D et al. (2012) A novel approach to recovery of function of mutant proteins by slowing down translation. J Biol Chem 287:34264-72
Oestreich, Kenneth J; Mohn, Sarah E; Weinmann, Amy S (2012) Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile. Nat Immunol 13:405-11
Oestreich, Kenneth J; Weinmann, Amy S (2012) Master regulators or lineage-specifying? Changing views on CD4+ T cell transcription factors. Nat Rev Immunol 12:799-804
Oestreich, Kenneth J; Weinmann, Amy S (2012) Encoding stability versus flexibility: lessons learned from examining epigenetics in T helper cell differentiation. Curr Top Microbiol Immunol 356:145-64
Oestreich, Kenneth J; Weinmann, Amy S (2012) Transcriptional mechanisms that regulate T helper 1 cell differentiation. Curr Opin Immunol 24:191-5
Oestreich, Kenneth J; Huang, Albert C; Weinmann, Amy S (2011) The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns. J Exp Med 208:1001-13
Smith, Heidi L; Monath, Thomas P; Pazoles, Pamela et al. (2011) Development of antigen-specific memory CD8+ T cells following live-attenuated chimeric West Nile virus vaccination. J Infect Dis 203:513-22
Miller, Sara A; Weinmann, Amy S (2010) Molecular mechanisms by which T-bet regulates T-helper cell commitment. Immunol Rev 238:233-46

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