This application requests support for years 29-34 of a predoctoral training program in Immunology at the University of Minnesota. During its long history, this training grant has served as a solid and consistent base of support for the highest quality graduate students in Immunology at the University of Minnesota. In doing so, it has played a key role in the development of the first University of Minnesota graduate program to feature Immunology, the recruitment of over 20 new immunology faculty, and the establishment of the multi- departmental Center for Immunology that now coordinates all University of Minnesota research and educational activities in this field. Most predoctoral students who seek training in Immunology enroll in the Microbiology, Immunology, and Cancer Biology (MICaB) Graduate Program. They take graduate level courses in cell and molecular biology and a rigorous semester-long foundational course designated Immunity and Immunopathology and an in- depth and intensive course called Current Topics in Immunology. Predoctoral students are chosen for this training grant usually in their second or third year of training, through a competitive selection process based on research productivity and potential. Once elected, students are supported for 2 years to conduct research in the laboratory of one of 22 preceptors whose interests broadly cover the field of Immunology. Supported students participate in research- in-progress meetings, journal clubs, and seminars featuring outside speakers. Trainees typically complete their research after 2-3 years, often publishing their work in high-impact journals, and then move on to postdoctoral training at top research institutions. The quality of the research produced by students supported by this training grant reflects an outstanding research environment, where faculty are highly invested in the success of trainees. This training grant is the only vehicle available at the University of Minnesota to enhance predoctoral-training in Immunology.
This training grant will support the career development of graduate students in immunology at the University of Minnesota. It is highly relevant to public health because these young scientists will produce tomorrow's new vaccines and cures for autoimmunity.
|Gartlan, Kate H; Bommiasamy, Hemamalini; Paz, Katelyn et al. (2018) A critical role for donor-derived IL-22 in cutaneous chronic GVHD. Am J Transplant 18:810-820|
|Beura, Lalit K; Mitchell, Jason S; Thompson, Emily A et al. (2018) Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory. Nat Immunol 19:173-182|
|Sjaastad, Louisa E; Fay, Elizabeth J; Fiege, Jessica K et al. (2018) Distinct antiviral signatures revealed by the magnitude and round of influenza virus replication in vivo. Proc Natl Acad Sci U S A 115:9610-9615|
|Owen, David L; Mahmud, Shawn A; Vang, Kieng B et al. (2018) Identification of Cellular Sources of IL-2 Needed for Regulatory T Cell Development and Homeostasis. J Immunol 200:3926-3933|
|Du, Jing; Flynn, Ryan; Paz, Katelyn et al. (2018) Murine chronic graft-versus-host disease proteome profiling discovers CCL15 as a novel biomarker in patients. Blood 131:1743-1754|
|Breed, Elise R; Lee, S Thera; Hogquist, Kristin A (2018) Directing T cell fate: How thymic antigen presenting cells coordinate thymocyte selection. Semin Cell Dev Biol 84:2-10|
|Beura, Lalit K; Wijeyesinghe, Sathi; Thompson, Emily A et al. (2018) T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells. Immunity 48:327-338.e5|
|Waring, Barbara M; Sjaastad, Louisa E; Fiege, Jessica K et al. (2018) MicroRNA-Based Attenuation of Influenza Virus across Susceptible Hosts. J Virol 92:|
|Guo, Liang; Sharma, Suresh D; Debes, Jose et al. (2018) The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts. Nucleic Acids Res 46:2537-2547|
|Kotov, Dmitri I; Kotov, Jessica A; Goldberg, Michael F et al. (2018) Many Th Cell Subsets Have Fas Ligand-Dependent Cytotoxic Potential. J Immunol 200:2004-2012|
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