Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI007464-04
Application #
2671569
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Project Start
1995-09-01
Project End
2000-08-31
Budget Start
1998-09-01
Budget End
1999-08-31
Support Year
4
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Rochester
Department
Pediatrics
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Tesini, Brenda L; Wright, Terry W; Malone, Jane E et al. (2017) Immunization with Pneumocystis Cross-Reactive Antigen 1 (Pca1) Protects Mice against Pneumocystis Pneumonia and Generates Antibody to Pneumocystis jirovecii. Infect Immun 85:
Butts, Arielle; Koselny, Kristy; Chabrier-Roselló, Yeissa et al. (2014) Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo. MBio 5:e00765-13
Kainth, Mundeep Kaur; Gigliotti, Francis (2014) Simultaneous testing of erythrocyte sedimentation rate and C-reactive protein: increased expenditure without demonstrable benefit. J Pediatr 165:625-7
Butts, Arielle; DiDone, Louis; Koselny, Kristy et al. (2013) A repurposing approach identifies off-patent drugs with fungicidal cryptococcal activity, a common structural chemotype, and pharmacological properties relevant to the treatment of cryptococcosis. Eukaryot Cell 12:278-87
Chabrier-Rosello, Yeissa; Gerik, Kimberly J; Koselny, Kristy et al. (2013) Cryptococcus neoformans phosphoinositide-dependent kinase 1 (PDK1) ortholog is required for stress tolerance and survival in murine phagocytes. Eukaryot Cell 12:12-22
Saputo, Sarah; Chabrier-Rosello, Yeissa; Luca, Francis C et al. (2012) The RAM network in pathogenic fungi. Eukaryot Cell 11:708-17
Nayak, Jennifer L; Sant, Andrea J (2012) Loss in CD4 T-cell responses to multiple epitopes in influenza due to expression of one additional MHC class II molecule in the host. Immunology 136:425-36
Bharucha, Nike; Chabrier-Rosello, Yeissa; Xu, Tao et al. (2011) A large-scale complex haploinsufficiency-based genetic interaction screen in Candida albicans: analysis of the RAM network during morphogenesis. PLoS Genet 7:e1002058
Nayak, Jennifer L; Richards, Katherine A; Chaves, Francisco A et al. (2010) Analyses of the specificity of CD4 T cells during the primary immune response to influenza virus reveals dramatic MHC-linked asymmetries in reactivity to individual viral proteins. Viral Immunol 23:169-80
Thingvoll, Erik S; Guillet, Ronnie; Caserta, Mary et al. (2008) Observational trial of a 48-hour gentamicin dosing regimen derived from Monte Carlo simulations in infants born at less than 28 weeks'gestation. J Pediatr 153:530-4

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