The goal of the Wisconsin Allergy Research Training (WISCART) program is to provide research training for postdoctoral fellows in Allergy and Immunology to prepare trainees for careers as independent academic research scientists. Objectives to achieve this goal include 1) to establish a high quality and productive research project, 2) to develop a progressive record of publication in respected research journals, 3) to obtain extramural grant funding during the fellowship, and 4) to have a minimum of 50% of the graduates of this program pursue a career in Allergy and Immunology research. There are generally 6-8 Allergy/immunology fellows in the UW program, and 4 fellows supported by the WISCART program. All fellows are MDs who have completed residency training in either Pediatrics or Internal Medicine. The first year of the program is funded by monies provided by the departmental and divisional funds, and is primarily clinical in nature. After the clinical year, the second and third years (2 positions per year), which are research intensive, are funded by WISCART. Additional years of training are encouraged, and are funded by research grants or other sources. The WISCART trainers are a diverse group of clinical, translational and basic scientists, and there are an exceptional number of opportunities for trainee research projects. The curriculum takes advantage of a number of institutional resources, including the University of Wisconsin Institute of Clinical and Translational Research, to provide comprehensive clinical research training, and optional advanced degree programs in clinical research.

Public Health Relevance

(See Instructions): Allergic diseases and asthma are among the most common diseases, and are increasing for reasons that are not well understood. The goal of this program is to provide training in clinical and translational research to physician scientists who wish to pursue careers devoted to research in these critical areas of unmet medical need.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI007635-12
Application #
8114994
Study Section
Allergy & Clinical Immunology-1 (AITC)
Program Officer
Prograis, Lawrence J
Project Start
2000-08-01
Project End
2015-08-31
Budget Start
2011-09-01
Budget End
2012-08-31
Support Year
12
Fiscal Year
2011
Total Cost
$172,681
Indirect Cost
Name
University of Wisconsin Madison
Department
Pediatrics
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
McDermott, Andrew J; Tumey, Tyler A; Huang, Mingwei et al. (2018) Inhaled Cryptococcus neoformans elicits allergic airway inflammation independent of Nuclear Factor Kappa B signalling in lung epithelial cells. Immunology 153:513-522
Hernández-Santos, Nydiaris; Wiesner, Darin L; Fites, J Scott et al. (2018) Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection. Cell Host Microbe 23:511-522.e5
Bønnelykke, Klaus; Coleman, Amaziah T; Evans, Michael D et al. (2018) Cadherin-related Family Member 3 Genetics and Rhinovirus C Respiratory Illnesses. Am J Respir Crit Care Med 197:589-594
Bashir, Hiba; Grindle, Kristine; Vrtis, Rose et al. (2018) Association of rhinovirus species with common cold and asthma symptoms and bacterial pathogens. J Allergy Clin Immunol 141:822-824.e9
Nanjappa, Som Gowda; McDermott, Andrew J; Fites, J Scott et al. (2017) Antifungal Tc17 cells are durable and stable, persisting as long-lasting vaccine memory without plasticity towards IFN? cells. PLoS Pathog 13:e1006356
Esquivel, Ann; Busse, William W (2017) Anaphylaxis Conundrum: A Trojan Horse Phenomenon. J Allergy Clin Immunol Pract 5:325-329
Esquivel, Ann; Busse, William W; Calatroni, Agustin et al. (2017) Effects of Omalizumab on Rhinovirus Infections, Illnesses, and Exacerbations of Asthma. Am J Respir Crit Care Med 196:985-992
Castillo, Jamee R; Peters, Stephen P; Busse, William W (2017) Asthma Exacerbations: Pathogenesis, Prevention, and Treatment. J Allergy Clin Immunol Pract 5:918-927
Hernández-Santos, Nydiaris; Klein, Bruce S (2017) Through the Scope Darkly: The Gut Mycobiome Comes into Focus. Cell Host Microbe 22:728-729
McDermott, Andrew J; Falkowski, Nicole R; McDonald, Roderick A et al. (2017) Role of interferon-? and inflammatory monocytes in driving colonic inflammation during acute Clostridium difficile infection in mice. Immunology 150:468-477

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