The Department of Immunology and Infectious Diseases (DIID) in the Division of Biologic Sciences (DBS) at the Harvard School of Public Health comprises a team of scientists who work on problems related to the immune response and to the biology, epidemiology and immunology of infectious diseases. The Division of Biological Science (DBS), established in 1993, is an umbrella structure that encompasses the biologic laboratory sciences in the areas of Immunology and Infectious Diseases. Cancer Cell Biology, Environmental Health, and Nutrition at the Harvard School of Public Health. The Ph.D. Program in Biological Sciences in Public Health (BPH) is located at the Harvard School of Public Health and is offered by the Faculty of Arts and Sciences of the Graduate School of Arts and Sciences. This predoctoral training grant application would support BPH students who choose to work in laboratories of faculty members of the Department of Immunology and Infectious Diseases. The BPH program provides an opportunity for training a cadre of investigators who, while possessing expertise in the individual fields of biological research, also possess a broad interdisciplinary knowledge of epidemiology and biostatistics. It has become increasingly evident that progress in disease prevention is optimally promoted by a close interaction between epidemiologis- ts and laboratory scientists, where laboratory discoveries and epidemio- logical observations interact in an iterative manner to advance research in both fields. Furthermore, basic biological and epidemiological discoveries must be placed in a wide social context. This program encourages active collaboration among scientists who share complementary interests in developing closer linkages between laboratory research and field work-all with an eye to developing innovative approaches to prevention.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Allergy & Clinical Immunology-1 (AITC)
Program Officer
Prograis, Lawrence J
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Harvard University
Schools of Public Health
United States
Zip Code
Hicks, Nathan D; Yang, Jian; Zhang, Xiaobing et al. (2018) Clinically prevalent mutations in Mycobacterium tuberculosis alter propionate metabolism and mediate multidrug tolerance. Nat Microbiol 3:1032-1042
Maiello, Pauline; DiFazio, Robert M; Cadena, Anthony M et al. (2018) Rhesus Macaques Are More Susceptible to Progressive Tuberculosis than Cynomolgus Macaques: a Quantitative Comparison. Infect Immun 86:
Cadena, Anthony M; Fortune, Sarah M; Flynn, JoAnne L (2017) Heterogeneity in tuberculosis. Nat Rev Immunol 17:691-702
Cadena, Anthony M; Flynn, JoAnne L; Fortune, Sarah M (2016) The Importance of First Impressions: Early Events in Mycobacterium tuberculosis Infection Influence Outcome. MBio 7:e00342-16
Layre, Emilie; Lee, Ho Jun; Young, David C et al. (2014) Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c. Proc Natl Acad Sci U S A 111:2978-83
Aguilar, Ruth; Magallon-Tejada, Ariel; Achtman, Ariel H et al. (2014) Molecular evidence for the localization of Plasmodium falciparum immature gametocytes in bone marrow. Blood 123:959-66
Rooks, Michelle G; Veiga, Patrick; Wardwell-Scott, Leslie H et al. (2014) Gut microbiome composition and function in experimental colitis during active disease and treatment-induced remission. ISME J 8:1403-17
McGee, Kathleen; Haim, Hillel; Korioth-Schmitz, Birgit et al. (2014) The selection of low envelope glycoprotein reactivity to soluble CD4 and cold during simian-human immunodeficiency virus infection of rhesus macaques. J Virol 88:21-40
Lin, Philana Ling; Ford, Christopher B; Coleman, M Teresa et al. (2014) Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing. Nat Med 20:75-9
Chao, Michael C; Pritchard, Justin R; Zhang, Yanjia J et al. (2013) High-resolution definition of the Vibrio cholerae essential gene set with hidden Markov model-based analyses of transposon-insertion sequencing data. Nucleic Acids Res 41:9033-48

Showing the most recent 10 out of 45 publications