Project Start
1978-07-01
Project End
1988-06-30
Budget Start
1985-07-01
Budget End
1986-06-30
Support Year
8
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Washington University
Department
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Frisch, S M; Reich, R; Collier, I E et al. (1990) Adenovirus E1A represses protease gene expression and inhibits metastasis of human tumor cells. Oncogene 5:75-83
Goldberg, G I; Frisch, S M; He, C et al. (1990) Secreted proteases. Regulation of their activity and their possible role in metastasis. Ann N Y Acad Sci 580:375-84
Winberg, J O; Gedde-Dahl Jr, T; Bauer, E A (1989) Collagenase expression in skin fibroblasts from families with recessive dystrophic epidermolysis bullosa. J Invest Dermatol 92:82-5
HE, C S; Wilhelm, S M; Pentland, A P et al. (1989) Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc Natl Acad Sci U S A 86:2632-6
Collier, I E; Smith, J; Kronberger, A et al. (1988) The structure of the human skin fibroblast collagenase gene. J Biol Chem 263:10711-3
Collier, I E; Wilhelm, S M; Eisen, A Z et al. (1988) H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen. J Biol Chem 263:6579-87
Bauer, E A; Tabas, M (1988) A perspective on the role of collagenase in recessive dystrophic epidermolysis bullosa. Arch Dermatol 124:734-6
Bauer, E A; Uitto, J; Tan, E M et al. (1988) Werner's syndrome. Evidence for preferential regional expression of a generalized mesenchymal cell defect. Arch Dermatol 124:90-101
Grant, G A; Eisen, A Z; Marmer, B L et al. (1987) The activation of human skin fibroblast procollagenase. Sequence identification of the major conversion products. J Biol Chem 262:5886-9
Wilhelm, S M; Collier, I E; Kronberger, A et al. (1987) Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells. Proc Natl Acad Sci U S A 84:6725-9

Showing the most recent 10 out of 27 publications