Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32AR007108-24
Application #
2700161
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Project Start
1975-07-01
Project End
2000-04-30
Budget Start
1998-05-01
Budget End
1999-04-30
Support Year
24
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Dam, Elizabeth M; Maier, Alison C; Hocking, Anne M et al. (2018) Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis. Front Immunol 9:1978
Gorman, Jacquelyn A; Hundhausen, Christian; Errett, John S et al. (2017) The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity. Nat Immunol 18:744-752
Sontheimer, Clayton; Liggitt, Denny; Elkon, Keith B (2017) Ultraviolet B Irradiation Causes Stimulator of Interferon Genes-Dependent Production of Protective Type I Interferon in Mouse Skin by Recruited Inflammatory Monocytes. Arthritis Rheumatol 69:826-836
Gazitt, Tal; Lood, Christian; Elkon, Keith B (2016) Citrullination in Rheumatoid Arthritis-A Process Promoted by Neutrophil Lysis? Rambam Maimonides Med J 7:
Buechler, Matthew B; Akilesh, Holly M; Hamerman, Jessica A (2016) Cutting Edge: Direct Sensing of TLR7 Ligands and Type I IFN by the Common Myeloid Progenitor Promotes mTOR/PI3K-Dependent Emergency Myelopoiesis. J Immunol 197:2577-82
Dam, Elizabeth M; Habib, Tania; Chen, Janice et al. (2016) The BANK1 SLE-risk variants are associated with alterations in peripheral B cell signaling and development in humans. Clin Immunol 173:171-180
Jackson, Shaun W; Jacobs, Holly M; Arkatkar, Tanvi et al. (2016) B cell IFN-? receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6. J Exp Med 213:733-50
Shenoi, Susan; Bell, Samantha; Wallace, Carol A et al. (2015) Juvenile idiopathic arthritis in relation to maternal prenatal smoking. Arthritis Care Res (Hoboken) 67:725-30
Elkon, Keith B; Sontheimer, Clayton (2014) Editorial: toll-like receptor 7: more than skin deep? Arthritis Rheumatol 66:481-4
Jackson, Shaun W; Scharping, Nicole E; Kolhatkar, Nikita S et al. (2014) Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation. J Immunol 192:4525-32

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