Abstract

The purpose of this program is to prepare individuals for research and training in the broad area of rheumatology. The major effort will be directed to the training of M.D.'s both in clinical rheumatology and a laboratory discipline so that they can assume responsible positions in rheumatology divisions in a medical school. Each fellow will be expected to become proficient in all areas of clinical rheumatology and, in addition, to acquire an in-depth training in immunology cell biology, electron microscopy, or biochemistry. Because of the nature of our staff, we also attract a number of Ph.D.'s for training in our laboratories. It is our hope that many of them, too, will continue their interest in the rheumatic diseases and will apply their skills in the future to studies in this area. In addition, we are responsible for the training of students, house staff, and postgraduate physicians in rheumatic diseases and basic sciences related to them.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32AR007176-24
Application #
2700165
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Project Start
1976-07-01
Project End
2001-04-30
Budget Start
1998-05-01
Budget End
1999-04-30
Support Year
24
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
New York University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016

  Publications

Howard, Rennie G; Samuels, Jonathan; Gyftopoulos, Soterios et al. (2015) Presence of gout is associated with increased prevalence and severity of knee osteoarthritis among older men: results of a pilot study. J Clin Rheumatol 21:63-71
Attur, Mukundan; Ben-Artzi, Ami; Yang, Qing et al. (2012) Perturbation of nuclear lamin A causes cell death in chondrocytes. Arthritis Rheum 64:1940-9
Crittenden, Daria B; Lehmann, R Aaron; Schneck, Laura et al. (2012) Colchicine use is associated with decreased prevalence of myocardial infarction in patients with gout. J Rheumatol 39:1458-64
Howard, Rennie G; Pillinger, Michael H; Gyftopoulos, Soterios et al. (2011) Reproducibility of musculoskeletal ultrasound for determining monosodium urate deposition: concordance between readers. Arthritis Care Res (Hoboken) 63:1456-62
Keenan, Robert T; O'Brien, William R; Lee, Kristen H et al. (2011) Prevalence of contraindications and prescription of pharmacologic therapies for gout. Am J Med 124:155-63
Attur, Mukundan G; Palmer, Glyn D; Al-Mussawir, Hayf E et al. (2009) F-spondin, a neuroregulatory protein, is up-regulated in osteoarthritis and regulates cartilage metabolism via TGF-beta activation. FASEB J 23:79-89
Attur, Mukundan; Al-Mussawir, Hayf E; Patel, Jyoti et al. (2008) Prostaglandin E2 exerts catabolic effects in osteoarthritis cartilage: evidence for signaling via the EP4 receptor. J Immunol 181:5082-8
Park, Jean Y; Pillinger, Michael H; Abramson, Steven B (2006) Prostaglandin E2 synthesis and secretion: the role of PGE2 synthases. Clin Immunol 119:229-40
Pillinger, Michael H; Rosenthal, Pamela B; Tolani, Sonia N et al. (2003) Cyclooxygenase-2-derived E prostaglandins down-regulate matrix metalloproteinase-1 expression in fibroblast-like synoviocytes via inhibition of extracellular signal-regulated kinase activation. J Immunol 171:6080-9
Capodici, C; Hanft, S; Feoktistov, M et al. (1998) Phosphatidylinositol 3-kinase mediates chemoattractant-stimulated, CD11b/CD18-dependent cell-cell adhesion of human neutrophils: evidence for an ERK-independent pathway. J Immunol 160:1901-9

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