In 1960, a research training program was established by the Department of Dermatology at NYU supported by the National institute of Arthritis and Metabolic Diseases """"""""to train physicians and scientists planning to enter a full-time career in dermatology, venerology or related fields of medicine or basic science"""""""". Our goal three and one-half decades later remains essentially the same. We propose to continue to use the facilities of our department and the departments of our colleagues to develop M.D., M.D./Ph.D., or Ph.D. academicians in order to insure that the exciting scientific progress which has been made during the past decade in skin disease-related research continues. Our focus will be research fellowship training for 2 to 3 years under the direct supervision of one of the more than 20 highly qualified preceptors in the departments of dermatology, biochemistry, cell biology, microbiology, pathology and pharmacology at NYU. Among the areas currently under active investigation and available for our trainees are pathways of pigmentation; cell biology and molecular biology of epithelium including epidermis and hair; basic and clinical cutaneous oncology, including AIDS research; various aspects of immunodermatology; proteases and angiogenesis; basic and clinical dermatopharmacology; cutaneous virology; and dermatopathology. All of our preceptors have made well- recognized contributions and, because of them, our department ranks among the major dermatologic training centers in our country. In addition to the research training, which is enhanced by our Sulzberger Scholars Program and the Skirball Institute of Biomolecular Medicine, our trainees will participate in research-related clinical activities and in the didactic and seminar programs of the Department of Dermatology and related departments. They may pursue formal courses in the Sackler Institute of Graduate Biomedical Sciences, the School of Medicine or elsewhere in the University. M.D. trainees will be chosen during or following their clinical training. The major criterion for selection will be a firm commitment to a career in academic dermatology since all of our residency applicants are intellectually capable of such careers. The major criterion for appointment of Ph.D. and M.D./Ph.D. trainees will also be commitment; in this case, to a career in basic studies related to skin diseases-related problems.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32AR007190-25
Application #
2909747
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Program Officer
Moshell, Alan N
Project Start
1976-07-01
Project End
2001-04-30
Budget Start
1999-05-01
Budget End
2000-04-30
Support Year
25
Fiscal Year
1999
Total Cost
Indirect Cost
Name
New York University
Department
Dermatology
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
Yancovitz, Molly; Litterman, Adam; Yoon, Joanne et al. (2012) Intra- and inter-tumor heterogeneity of BRAF(V600E))mutations in primary and metastatic melanoma. PLoS One 7:e29336
Yancovitz, Molly; Yoon, Joanne; Mikhail, Maryann et al. (2007) Detection of mutant BRAF alleles in the plasma of patients with metastatic melanoma. J Mol Diagn 9:178-83
Yancovitz, Molly; Finelt, Nika; Warycha, Melanie A et al. (2007) Role of radiologic imaging at the time of initial diagnosis of stage T1b-T3b melanoma. Cancer 110:1107-14
Wang, Xuan; Bolotin, Diana; Chu, David H et al. (2006) AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis. J Cell Biol 172:409-21
Hall, Andrea M; Krishnamoorthy, Lalitha; Orlow, Seth J (2004) 25-hydroxycholesterol acts in the Golgi compartment to induce degradation of tyrosinase. Pigment Cell Res 17:396-406
Hall, Andrea M; Krishnamoorthy, Lalitha; Orlow, Seth J (2003) Accumulation of tyrosinase in the endolysosomal compartment is induced by U18666A. Pigment Cell Res 16:149-58
Nikonov, A V; Kreibich, G (2003) Organization of translocon complexes in ER membranes. Biochem Soc Trans 31:1253-6
Nikonov, Andrei V; Snapp, Erik; Lippincott-Schwartz, Jennifer et al. (2002) Active translocon complexes labeled with GFP-Dad1 diffuse slowly as large polysome arrays in the endoplasmic reticulum. J Cell Biol 158:497-506
Shen, B; Rosenberg, B; Orlow, S J (2001) Intracellular distribution and late endosomal effects of the ocular albinism type 1 gene product: consequences of disease-causing mutations and implications for melanosome biogenesis. Traffic 2:202-11
Shen, B; Samaraweera, P; Rosenberg, B et al. (2001) Ocular albinism type 1: more than meets the eye. Pigment Cell Res 14:243-8

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