EXCEED THESPACE PROVIDED. In 1960, a research training program was established jn the Department of Dermatology and Syphilology at NYU supported by the National Institue of Arthritis and Metabolic Diseases 'to train physicians and scientists planning to enter a full time career in dermatology,venereology or related fields of medicineor basic science.' Although the name of the Department and that of the NIH Institute have changed, thebroad, ong-term objectives of our program remain.essentially unchanged. We shall use the facilities of our department as well as those of the school and other departments in New York City to train M.D., M.D./Ph.D., or Ph.D. academicians to insure the continuation of the excitingscientific progress that has been made in skin biology and skin disease related research during the past four decades. Our specific focused goal will be to provide postdoctoral researchtraining of 2-3 years duration under the direct supervision of one of the highly qualified mentors in our department, in other departments atNYU School of Medicine, or in other NYC academicinstitutions. Trainees may participate in our ongoing research in areas including cellular and molecular biology of melanocytes, cell and molecular biology of epithelium, basic and clinical cutaneous oncology, immunodermatology, wound healing, clinicaldermatopharmacology, and dermatopathology All of the mentors in our program have made well recognized contributions and because of the quality of our faculty, NYU dermatology has ranked among the major dermatologic training centers in the world. The strength of our clinical program and the volume of patient care activities enhances the exposureof trainees to patient-centered problems and assurestheir ability to perform translational research. M.D. trainees, as part of our Sulzberger Scholars Program, will be chosen during their last year of clinical training. The major criterion for selection will be a firm commitment to a career in academic dermatology. Themajor criterion for appointment of Ph.D. trainees will also be commitment; in this case, to a career in basic studies related to skin and skin diseases. Although many may consider such disease superficial and trivial,recent interest, mandated by Congress, on the Burden of Skin Disease has shown how important these diseases are to patients and to public health in general. PERFORMANCE SITE ========================================Section End===========================================

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32AR007190-31
Application #
6882675
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Program Officer
Baker, Carl
Project Start
1976-07-01
Project End
2007-04-30
Budget Start
2005-05-01
Budget End
2007-04-30
Support Year
31
Fiscal Year
2005
Total Cost
$168,026
Indirect Cost
Name
New York University
Department
Dermatology
Type
Schools of Medicine
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Yancovitz, Molly; Litterman, Adam; Yoon, Joanne et al. (2012) Intra- and inter-tumor heterogeneity of BRAF(V600E))mutations in primary and metastatic melanoma. PLoS One 7:e29336
Yancovitz, Molly; Finelt, Nika; Warycha, Melanie A et al. (2007) Role of radiologic imaging at the time of initial diagnosis of stage T1b-T3b melanoma. Cancer 110:1107-14
Yancovitz, Molly; Yoon, Joanne; Mikhail, Maryann et al. (2007) Detection of mutant BRAF alleles in the plasma of patients with metastatic melanoma. J Mol Diagn 9:178-83
Wang, Xuan; Bolotin, Diana; Chu, David H et al. (2006) AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis. J Cell Biol 172:409-21
Hall, Andrea M; Krishnamoorthy, Lalitha; Orlow, Seth J (2004) 25-hydroxycholesterol acts in the Golgi compartment to induce degradation of tyrosinase. Pigment Cell Res 17:396-406
Hall, Andrea M; Krishnamoorthy, Lalitha; Orlow, Seth J (2003) Accumulation of tyrosinase in the endolysosomal compartment is induced by U18666A. Pigment Cell Res 16:149-58
Nikonov, A V; Kreibich, G (2003) Organization of translocon complexes in ER membranes. Biochem Soc Trans 31:1253-6
Nikonov, Andrei V; Snapp, Erik; Lippincott-Schwartz, Jennifer et al. (2002) Active translocon complexes labeled with GFP-Dad1 diffuse slowly as large polysome arrays in the endoplasmic reticulum. J Cell Biol 158:497-506
Shen, B; Rosenberg, B; Orlow, S J (2001) Intracellular distribution and late endosomal effects of the ocular albinism type 1 gene product: consequences of disease-causing mutations and implications for melanosome biogenesis. Traffic 2:202-11
Shen, B; Samaraweera, P; Rosenberg, B et al. (2001) Ocular albinism type 1: more than meets the eye. Pigment Cell Res 14:243-8

Showing the most recent 10 out of 38 publications