This is a competitive renewal of the rheumatology training program at Boston University School of Medicine. This training grant was competitively renewed successfully in May 2009 under the directorship of Dr. David Felson. Under Dr. Felson's leadership and the active involvement of faculty in rheumatology and other departments, the training program is vibrant and actively training rheumatologists and others to enter academic careers in both clinical and bench laboratory research. The majority of our previously supported trainees have entered academic medicine and most of these, in addition to, or after their T32 support, have successfully competed for funding for their own career development grants. Even others in this training program not supported by T32 have evidenced academic success with high rates of funding and other milestones of academic success. We have trained MD and PhD postdoctoral trainees. There is a prominent clinical research component to this training grant with at least half of fellows pursuing a clinical research track which includes taking courses toward a degree in our School of Public Health and participating in the Boston University CTSI training program. The parent department is funded by two Center grants from NIAMS (CORT and MCRC) in addition to other NIH and private foundation funding. We take advantage of the breadth of bench laboratory experience and excellence at Boston University and of one of the leading clinical research groups in rheumatology to permit our trainees interested in research to train with outstanding scientists doing work of relevance to rheumatic diseases. Among unique elements of our training program are the inclusion of doctorally trained physical therapists as postdoctoral clinical research trainees. The training program is enhanced with the recent recruitment of two outstanding senior scientists Dr. Hyon Choi, a leading arthritis epidemiologist and Dr. Maria Trojanowska, a leading scientist in fibroblast biology.

Public Health Relevance

This is a competitive renewal of the rheumatology training program at Boston University School of Medicine. The specific goals of this training program are to train rheumatologists, allied health professionals and PhD scientists in rheumatology clinical research and/or in bench science, the latter especially related to scleroderma. Most of the trainees supported in the last 2 cycles by this T32 grant have entered academic medicine, and most of them, in addition to their T32 support, have successfully competed for funding for their own career development grants.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32AR007598-20
Application #
9478841
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Program Officer
Mao, Su-Yau
Project Start
1997-05-01
Project End
2019-04-30
Budget Start
2018-05-01
Budget End
2019-04-30
Support Year
20
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Boston University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
Dai, Zhaoli; Zhang, Yuqing; Lu, Na et al. (2018) Association Between Dietary Fiber Intake and Bone Loss in the Framingham Offspring Study. J Bone Miner Res 33:241-249
Bacon, Kathryn L; Segal, Neil A; Ă˜iestad, Britt Elin et al. (2018) Thresholds in the relationship of quadriceps strength with functional limitations in women with knee osteoarthritis. Arthritis Care Res (Hoboken) :
Bacon, Kathryn L; Segal, Neil A; Ă˜iestad, Britt Elin et al. (2018) Concurrent change in quadriceps strength and physical function over 5 years in The Multicenter Osteoarthritis Study. Arthritis Care Res (Hoboken) :
Dai, Zhaoli; Felson, David T; Zhang, Yuqing (2017) Reply. Arthritis Care Res (Hoboken) 69:1932-1933
Dai, Zhaoli; Lu, Na; Niu, Jingbo et al. (2017) Dietary Fiber Intake in Relation to Knee Pain Trajectory. Arthritis Care Res (Hoboken) 69:1331-1339
White, D K; Tudor-Locke, C; Zhang, Y et al. (2016) Prospective change in daily walking over 2 years in older adults with or at risk of knee osteoarthritis: the MOST study. Osteoarthritis Cartilage 24:246-53
Mathes, Allison L; Rice, Lisa; Affandi, Alsya J et al. (2015) CpGB DNA activates dermal macrophages and specifically recruits inflammatory monocytes into the skin. Exp Dermatol 24:133-9
Han, Rong; Pacifici, Maurizio; Iwamoto, Masahiro et al. (2015) Endothelial Erg expression is required for embryogenesis and vascular integrity. Organogenesis 11:75-86
Mathes, Allison L; Christmann, Romy B; Stifano, Giuseppina et al. (2014) Global chemokine expression in systemic sclerosis (SSc): CCL19 expression correlates with vascular inflammation in SSc skin. Ann Rheum Dis 73:1864-72
van Bon, Lenny; Affandi, Alsya J; Broen, Jasper et al. (2014) Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis. N Engl J Med 370:433-43

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